Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | NAAA | Q02083 | 3/20 | 0.44 |
| ▸ | IDH1 | O75874 | 8/20 | 0.42 |
| ▸ | IL6ST | P40189 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15684256 | 1.00 | PPARA (0.44) | PPARANAAAIDH1IL6STFAAH | |
| SCHEMBL2869150 | 1.00 | PPARA (0.44) | PPARANAAAIDH1IL6STFAAH | |
| SCHEMBL6600116 | 0.88 | IL6ST (0.41) | PPARANAAAIDH1IL6STFAAH | |
| SCHEMBL5761604 | 0.88 | IL6ST (0.41) | PPARANAAAIDH1IL6STFAAH | |
| SCHEMBL1750168 | 0.86 | ALDH1A1 (0.55) | PPARANAAAIDH1IL6STFAAH | |
| SCHEMBL6454677 | 0.86 | NAAA (0.46) | PPARANAAAIDH1IL6STFAAH | |
| SCHEMBL5022256 | 0.86 | NAAA (0.46) | PPARANAAAIDH1IL6STFAAH | |
| SCHEMBL1750169 | 0.86 | ALDH1A1 (0.55) | PPARANAAAIDH1IL6STFAAH | |
| SCHEMBL3308447 | 0.84 | GRM5 (0.46) | NAAAIDH1FAAHALDH1A1 | |
| SCHEMBL3308451 | 0.84 | GRM5 (0.46) | NAAAIDH1FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| EP-1572203-A1 | SUBSTITUTED 4-ALKOXYOXAZOL DERIVATIVES AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-05-27 | — | — | US | disclosed |
| WO-2004041275-A1 | SUBSTITUTED 4-ALKOXYOXAZOL DERIVATIVES AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-21 | — | — | WO | disclosed |
| EP-1380562-A1 | CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | GPR119, IRS1, SLC5A1 | PPARA 339/4885NAAA 3045/4885IDH1 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.