Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19785906 | 0.84 | DPP4 (0.38) | DPP4PLD1HTR2CDPP7PSEN1 | |
| SCHEMBL15258053 | 0.84 | DPP4 (0.38) | DPP4PLD1HTR2CDPP7PSEN1 | |
| Hydrochloric Acid SCHEMBL15254308 | 0.83 | DPP4 (0.38) | DPP4PLD1HTR2CPSEN1PSEN2 | |
| Hydrochloric Acid SCHEMBL29613587 | 0.83 | DPP4 (0.38) | DPP4PLD1HTR2CPSEN1PSEN2 | |
| SCHEMBL324738 | 0.80 | RAB9A (0.48) | DPP4PLD1HTR2CDPP7PSEN1 | |
| SCHEMBL13758227 | 0.79 | DPP4 (0.35) | DPP4PLD1HTR2CPSEN1PSEN2 | |
| SCHEMBL31735994 | 0.79 | DPP4 (0.41) | DPP4PLD1DPP7ENPP2 | |
| SCHEMBL954848 | 0.79 | DPP4 (0.39) | DPP4HTR2CENPP2TSHR | |
| SCHEMBL953150 | 0.79 | DPP4 (0.39) | DPP4HTR2CENPP2TSHR | |
| SCHEMBL8206794 | 0.79 | DPP4 (0.39) | DPP4HTR2CENPP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569690-B2 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |