Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL953151 | 0.84 | DPP4 (0.39) | DPP4HTTTSHRALDH1A1GAA | |
| SCHEMBL954848 | 0.84 | DPP4 (0.39) | DPP4HTTTSHRALDH1A1GAA | |
| SCHEMBL953150 | 0.84 | DPP4 (0.39) | DPP4HTTTSHRALDH1A1GAA | |
| SCHEMBL8206794 | 0.84 | DPP4 (0.39) | DPP4HTTTSHRALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL17560457 | 0.83 | DPP4 (0.38) | DPP4HTTTSHRALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL17560459 | 0.83 | DPP4 (0.38) | DPP4HTTTSHRALDH1A1GAA | |
| SCHEMBL3713445 | 0.82 | RAB9A (0.46) | RAB9ADPP4HTTTSHRALDH1A1 | |
| SCHEMBL4813100 | 0.80 | DPP4 (0.40) | DPP4TSHRPLD1HTR2CPSEN1 | |
| SCHEMBL4327908 | 0.80 | DPP4 (0.39) | DPP4TSHRPLD1HTR2CDPP7 | |
| SCHEMBL18705712 | 0.80 | DPP4 (0.37) | DPP4TSHRPLD1HTR2CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590953-A1 | TETRAZOLE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | Convergence Pharmaceuticals Limited (GB) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004604-A1 | TETRAZOLE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | Convergence Pharmaceuticals Limited (GB) | 2012-01-12 | — | — | WO | disclosed |