Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.45 |
| ▸ | HTR1B | P28222 | 6/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643502 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL7643497 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL16106155 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL4329 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL137215 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL7291306 | 0.98 | HTR1D (0.44) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL7291301 | 0.98 | HTR1D (0.44) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL9433756 | 0.88 | HTR1D (0.39) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL3647546 | 0.83 | CACNA1C (0.50) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL15304333 | 0.83 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3353 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551050-B | Preparation method of zolmitriptan key intermediate | 湖北天义药业有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-114315749-B | Method for synthesizing aliskiren intermediate by continuous flow microreactor | 湖南华腾医药有限公司 | 2024-04-26 | — | — | CN | claimed |
| WO-2024040267-A2 | DIRECT SYNTHESIS OF N-(3-SUBSTITUTED-CHROMAN-4-YL)-7H- PYRROLO[2,3-D]PYRIMIDIN-4-AMINES AND DERIVATIVES THEREOF | MITOKININ, INC. (US) | 2024-02-22 | — | — | WO | claimed |
| CN-117551050-A | Preparation method of zolmitriptan key intermediate | 湖北天义药业有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-117186150-A | Preparation method of LFA-1 inhibitor | 维眸生物科技（上海）有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-113648429-B | Polymer for activating immunity by targeting tumor surrounding cells, and preparation method and application thereof | 中山大学 | 2023-11-10 | — | — | CN | claimed |
| CN-116874568-A | Synthesis method of valpromethazine | 中国人民解放军海军军医大学 | 2023-10-13 | — | — | CN | claimed |
| CN-112500361-B | Preparation method of (S) -4-phenyl-2-oxazolidinone | 甘肃瀚聚药业有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-111440046-B | Synthetic method of sex pheromone (S) -14-methyl-1-octadecene of lepidoptera pest phyllocladia persica | 塔里木大学 | 2022-09-16 | — | — | CN | claimed |
| CN-114315749-A | Method for synthesizing aliskiren intermediate by continuous flow microreactor | 湖南华腾医药有限公司 | 2022-04-12 | — | — | CN | claimed |
| WO-2002029001-A2 | NOVEL LYSOPHOSPHATIDIC ACID RECEPTOR AGONISTS AND ANTAGONISTS | UNIVERSITY OF VIRGINIAN PATENT FOUNDATION (US) | 2002-04-11 | — | — | WO | claimed |
| EP-1077926-A1 | PROPYLISOPROPYL ACETIC ACID AND PROPYLISOPROPYL ACETAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-02-28 | — | — | EP | claimed |
| EP-0966429-A1 | VALNOCTAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND SEPARATION AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1999-12-29 | — | — | EP | claimed |
| WO-1999054282-A1 | PROPYLISOPROPYL ACETIC ACID AND PROPYLISOPROPYL ACETAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY (IL) | 1999-10-28 | — | — | WO | claimed |
| EP-0911324-A1 | Process for the preparation of chiral succinic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-04-28 | — | — | EP | claimed |
| WO-1998030536-A1 | VALNOCTAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND SEPARATION AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1998-07-16 | — | — | WO | claimed |
| EP-0594608-B1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS | RES CORP TECHNOLOGIES INC (US) | 1997-10-15 | — | — | EP | claimed |
| EP-0594608-A1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. | RES CORP TECHNOLOGIES INC (US) | 1994-05-04 | — | — | EP | claimed |
| EP-0594608-A4 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. | RES CORP TECHNOLOGIES INC (US) | 1993-03-15 | — | — | EP | claimed |
| WO-1991014672-A1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-10-03 | — | — | WO | claimed |