Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.45 |
| ▸ | HTR1B | P28222 | 6/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643502 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL4328 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL16106155 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL4329 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL137215 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL7291306 | 0.98 | HTR1D (0.44) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL7291301 | 0.98 | HTR1D (0.44) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL9433756 | 0.88 | HTR1D (0.39) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL3647546 | 0.83 | CACNA1C (0.50) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL15304333 | 0.83 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099227-A1 | Processesand intermediatesfor preparing substitutedchromanol derivatives | PISCOPIO ANTHONY (US) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099227-A1 | Processesand intermediatesfor preparing substitutedchromanol derivatives | CYP11B1, CYP11B2, CYP51A1 | HTR1D 894/4885HTR1B 2286/4885HTR1A 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.