Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.39 |
| ▸ | HTR1B | P28222 | 6/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643502 | 0.88 | HTR1D (0.45) | HTR1DHTR1BSCN9AHTR1AHTR2A | |
| SCHEMBL7643497 | 0.88 | HTR1D (0.45) | HTR1DHTR1BSCN9AHTR1AHTR2A | |
| SCHEMBL4329 | 0.88 | HTR1D (0.45) | HTR1DHTR1BSCN9AHTR1AHTR2A | |
| SCHEMBL4328 | 0.88 | HTR1D (0.45) | HTR1DHTR1BSCN9AHTR1AHTR2A | |
| SCHEMBL137215 | 0.88 | HTR1D (0.45) | HTR1DHTR1BSCN9AHTR1AHTR2A | |
| SCHEMBL16106155 | 0.88 | HTR1D (0.45) | HTR1DHTR1BSCN9AHTR1AHTR2A | |
| SCHEMBL7291301 | 0.87 | HTR1D (0.44) | HTR1DHTR1BSCN9AHTR1AHTR2A | |
| SCHEMBL27360323 | 0.87 | HTR1D (0.44) | HTR1DHTR1BSCN9AHTR1AHTR2A | |
| SCHEMBL7291306 | 0.87 | HTR1D (0.44) | HTR1DHTR1BSCN9AHTR1AHTR2A | |
| SCHEMBL26773129 | 0.80 | HTR1D (0.44) | HTR1DHTR1BSCN9AHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281585-A | Secondary amide containing antagonist | MERCK & CO., INC. (US) | 1994-01-25 | — | — | US | disclosed |