Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.45 |
| ▸ | HTR1B | P28222 | 6/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643502 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL4328 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL7643497 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL16106155 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL137215 | 1.00 | HTR1D (0.45) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL7291306 | 0.98 | HTR1D (0.44) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL7291301 | 0.98 | HTR1D (0.44) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL9433756 | 0.88 | HTR1D (0.39) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL3647546 | 0.83 | CACNA1C (0.50) | HTR1DHTR1BHTR1AHTR2AKMT2A | |
| SCHEMBL15304333 | 0.83 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3283 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040267-A2 | DIRECT SYNTHESIS OF N-(3-SUBSTITUTED-CHROMAN-4-YL)-7H- PYRROLO[2,3-D]PYRIMIDIN-4-AMINES AND DERIVATIVES THEREOF | MITOKININ, INC. (US) | 2024-02-22 | — | — | WO | claimed |
| CN-114516866-B | Preparation method of chiral 4-alkyl-pyrrole-3-formic acid compound | 南京卓康医药科技有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-117551050-A | Preparation method of zolmitriptan key intermediate | 湖北天义药业有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-117186150-A | Preparation method of LFA-1 inhibitor | 维眸生物科技（上海）有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-116874568-A | Synthesis method of valpromethazine | 中国人民解放军海军军医大学 | 2023-10-13 | — | — | CN | claimed |
| CN-112500361-B | Preparation method of (S) -4-phenyl-2-oxazolidinone | 甘肃瀚聚药业有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-113185505-B | Quinolone oxazolidinone compound and preparation method and application thereof | 中国农业大学 | 2022-09-27 | — | — | CN | claimed |
| CN-115074404-A | Synthesis method of (2R, 4R) -2-amino-4-methylnonanoic acid | 吉尔多肽生物制药(大连市)有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-111440046-B | Synthetic method of sex pheromone (S) -14-methyl-1-octadecene of lepidoptera pest phyllocladia persica | 塔里木大学 | 2022-09-16 | — | — | CN | claimed |
| CN-112939848-B | Preparation method of bupivacaine and intermediate (S) -2-piperidinecarboxylic acid thereof | 浙江工业大学 | 2022-07-01 | — | — | CN | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5561227-A | CHLORINATION A CARBOXYLIC ACID; DEPROTONATION A CHIRAL (OXA OR THIA)ZOLIDINONE; ENOLIZING; CYCLIZATION | SCHERING CORPORATION (US) | 1996-10-01 | — | — | US | claimed |
| US-5536826-A | OXAZOLIDINONE OR DERIVATIVE | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1996-07-16 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0673784-A2 | Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
| EP-0672687-A1 | Process for producing amino-functional cyclodextrin derivatives | Consortium für elektrochemische Industrie GmbH (DE) | 1995-09-20 | — | — | EP | claimed |
| US-5306817-A | Multistep; cyclizing a hydroxyamide by treating with a dialkylchlorophosphate either a metal hydride, or an aqueous solution of base and a phase transfer catalyst | SCHERING CORPORATION (US) | 1994-04-26 | — | — | US | claimed |
| EP-0378657-B1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS | RAJADHYAKSHA VITHAL J (US) | 1994-02-02 | — | — | EP | claimed |
| US-4960771-A | TRANSDERMAL DELIVERY OF THERAPEUTIC AGENTS; DRUGS, SUNSCREENS, INSECT REPELLENTS, COSMETICS | LVMH MOET HENNESSY LOUIS VUITTON, INC. | 1990-10-02 | — | — | US | claimed |