Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 14/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329052 | 0.85 | ERN1 (0.50) | ERN1RAB9A | |
| SCHEMBL7137309 | 0.85 | ERN1 (0.52) | ERN1RAB9A | |
| SCHEMBL3967175 | 0.76 | HDAC4 (0.61) | ERN1HDAC4HDAC2HDAC8GSTP1 | |
| SCHEMBL12492120 | 0.74 | ERN1 (0.69) | ERN1MEN1KMT2A | |
| SCHEMBL31406989 | 0.73 | GSTP1 (0.57) | ERN1HDAC4HDAC2HDAC8MEN1 | |
| SCHEMBL31406988 | 0.73 | GSTP1 (0.57) | ERN1HDAC4HDAC2HDAC8MEN1 | |
| SCHEMBL868484 | 0.73 | GSTP1 (0.57) | ERN1HDAC4HDAC2HDAC8MEN1 | |
| SCHEMBL27493423 | 0.72 | PTPN1 (0.48) | ERN1MEN1KMT2A | |
| SCHEMBL7643584 | 0.72 | HDAC4 (0.55) | ERN1HDAC4HDAC2HDAC8GSTP1 | |
| SCHEMBL8365467 | 0.70 | ALDH1A1 (0.50) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141236-A1 | SPIROPYRANS HAVING FLUOROPHORIC GROUPS | BASF SE (DE) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009141236-A1 | SPIROPYRANS HAVING FLUOROPHORIC GROUPS | BASF SE (DE) | 2009-11-26 | — | — | WO | disclosed |