Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7137309 | 0.97 | ERN1 (0.52) | ERN1CRHBPCRHR2ELANEPOLB | |
| SCHEMBL4328147 | 0.85 | ERN1 (0.48) | ERN1RAB9A | |
| SCHEMBL2437022 | 0.83 | CRHBP (0.55) | CRHBPCRHR2ELANEPOLBMAPK1 | |
| SCHEMBL4262386 | 0.80 | PTGS2 (0.52) | ERN1CRHBPCRHR2ELANEPOLB | |
| SCHEMBL27493423 | 0.80 | PTPN1 (0.48) | ERN1ELANEPOLB | |
| SCHEMBL2790318 | 0.78 | PTPN1 (0.56) | ERN1 | |
| SCHEMBL12492120 | 0.78 | ERN1 (0.69) | ERN1MAPK1 | |
| SCHEMBL7930381 | 0.77 | ERN1 (0.56) | ERN1CRHBPCRHR2ELANEPOLB | |
| SCHEMBL11671011 | 0.77 | CRHBP (0.62) | CRHBPCRHR2POLBMAPK1PTGS2 | |
| SCHEMBL22658133 | 0.76 | MEN1 (0.62) | CRHBPCRHR2ELANEPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141236-A1 | SPIROPYRANS HAVING FLUOROPHORIC GROUPS | BASF SE (DE) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009141236-A1 | SPIROPYRANS HAVING FLUOROPHORIC GROUPS | BASF SE (DE) | 2009-11-26 | — | — | WO | disclosed |