Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316901 | 0.92 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3DRD1DRD5 | |
| SCHEMBL4457705 | 0.85 | MAOA (0.34) | SLC6A4 | |
| SCHEMBL4566736 | 0.79 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3DRD1HRH3 | |
| SCHEMBL18034982 | 0.69 | SLC6A4 (0.62) | SLC6A4SLC6A2SLC6A3SIGMAR1DRD1 | |
| SCHEMBL4318796 | 0.67 | DRD1 (0.50) | SLC6A4SLC6A2SLC6A3DRD1DRD5 | |
| SCHEMBL18034954 | 0.66 | SLC6A4 (0.62) | SLC6A4SLC6A2SLC6A3SIGMAR1DRD1 | |
| SCHEMBL16624303 | 0.66 | SLC6A2 (0.62) | SLC6A4SLC6A2SLC6A3SIGMAR1DRD1 | |
| SCHEMBL4316512 | 0.66 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL6482800 | 0.65 | SLC6A2 (0.60) | SLC6A4SLC6A2SLC6A3SIGMAR1DRD1 | |
| SCHEMBL4459508 | 0.65 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |