Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181136 | 0.85 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3MTNR1BSIRT1 | |
| SCHEMBL18034982 | 0.80 | SLC6A4 (0.62) | SLC6A2SLC6A4SLC6A3SIGMAR1DRD1 | |
| SCHEMBL6493845 | 0.80 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1GAA | |
| SCHEMBL1520733 | 0.79 | SIRT1 (0.45) | MTNR1BSIRT1MTNR1A | |
| SCHEMBL1842495 | 0.77 | MTNR1A (0.56) | MTNR1BMTNR1A | |
| SCHEMBL30746730 | 0.77 | MTNR1A (0.56) | MTNR1BMTNR1A | |
| SCHEMBL16624303 | 0.77 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3SIGMAR1DRD1 | |
| SCHEMBL18034954 | 0.77 | SLC6A4 (0.62) | SLC6A2SLC6A4SLC6A3SIGMAR1DRD1 | |
| SCHEMBL12699778 | 0.76 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL9628615 | 0.75 | MTNR1A (0.54) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256164-A1 | NK1 and NK3 antagonists | PFIZER INC | 2005-11-17 | — | — | US | claimed |
| US-20050256164-A1 | NK1 and NK3 antagonists | PFIZER INC | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256164-A1 | NK1 and NK3 antagonists | TAC3, TACR1, TACR2 | SLC6A2 628/4885SLC6A4 491/4885SLC6A3 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.