Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334764 | 0.84 | GPR119 (0.58) | GPR119KCNH2SCD | |
| SCHEMBL12391222 | 0.78 | GPR119 (0.61) | GPR119KCNH2SCD | |
| SCHEMBL11954469 | 0.76 | GPR119 (0.61) | GPR119KCNH2SCD | |
| SCHEMBL2332938 | 0.75 | GPR119 (0.69) | GPR119KCNH2SCD | |
| SCHEMBL2333652 | 0.72 | GPR119 (0.65) | GPR119KCNH2SCDGPR6 | |
| SCHEMBL2335683 | 0.70 | GPR119 (0.63) | GPR119KCNH2SCD | |
| SCHEMBL12391230 | 0.70 | GPR119 (0.65) | GPR119KCNH2SCDGPR6 | |
| SCHEMBL2337468 | 0.70 | GPR119 (0.63) | GPR119KCNH2SCDGPR6 | |
| SCHEMBL2336374 | 0.70 | GPR119 (0.64) | GPR119KCNH2GPR6 | |
| SCHEMBL2338755 | 0.68 | GPR119 (0.71) | GPR119KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023702-A1 | PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY | 2009-01-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023702-A1 | PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | GPR119, GPR65, GPR27 | GPR119 1/4885KCNH2 1362/4885SCD 2650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.