Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329185 | 1.00 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BMAOBLMNA | |
| SCHEMBL4331636 | 0.90 | ACHE (0.48) | MAOBLMNAHTTPOLB | |
| SCHEMBL4331638 | 0.90 | ACHE (0.48) | MAOBLMNAHTTPOLB | |
| SCHEMBL4336715 | 0.88 | MAOB (0.44) | MAOBLMNAHTTPOLBKDM4E | |
| SCHEMBL4336713 | 0.88 | MAOB (0.44) | MAOBLMNAHTTPOLBKDM4E | |
| SCHEMBL4331045 | 0.87 | MAOB (0.46) | ADRA1DADRA1AADRA1BMAOBMAPT | |
| SCHEMBL4331046 | 0.87 | MAOB (0.46) | ADRA1DADRA1AADRA1BMAOBMAPT | |
| SCHEMBL4338757 | 0.87 | ACHE (0.46) | MAOBLMNAHTTPOLB | |
| SCHEMBL4338750 | 0.87 | ACHE (0.46) | MAOBLMNAHTTPOLB | |
| SCHEMBL4326677 | 0.83 | MAOB (0.44) | ADRA1DADRA1AADRA1BMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285849-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2009-11-19 | — | — | US | disclosed |
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-20050069555-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285849-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | MAVS, IRF3, HAVCR2 | ADRA1D 3854/4885ADRA1A 3245/4885ADRA1B 1425/4885 |
| US-20050069555-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | MAVS, IRF3, HAVCR2 | ADRA1D 3547/4885ADRA1A 3037/4885ADRA1B 1390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.