SCHEMBL4329344

SCHEMBL4329344

CC(=O)O[C@@H]1[C@H](O)[C@@H](COP(=O)(OC[C@@H](O)[C@@H](O)[C@@H](O)C=O)OP(=O)(O)O)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RNASEL Q05823 5/20 0.55
P2RX1 P51575 3/20 0.54
P2RX3 P56373 3/20 0.54
P2RY11 Q96G91 2/20 0.54
P2RX2 Q9UBL9 2/20 0.54
P2RX6 O15547 1/20 0.54
P2RX5 Q93086 1/20 0.54
P2RX4 Q99571 1/20 0.54
P2RX7 Q99572 1/20 0.54
P2RY1 P47900 3/20 0.53
DNPH1 O43598 1/20 0.53
PRKAB2 O43741 1/20 0.53
TRPM2 O94759 1/20 0.53
LDHA P00338 1/20 0.53
ADRB2 P07550 1/20 0.53
FBP1 P09467 1/20 0.53
SRC P12931 1/20 0.53
ADORA1 P30542 1/20 0.53
P2RY2 P41231 1/20 0.53
PRKAG1 P54619 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375102 0.92 RNASEL (0.61) RNASELP2RX1P2RX3P2RY11P2RX2
SCHEMBL1526121 0.90 P2RY1 (0.66) RNASELP2RX1P2RX3P2RY11P2RX2
Xylose SCHEMBL14157064 0.89 RNASEL (0.62) RNASELP2RX1P2RX3P2RY11P2RX2
SCHEMBL32662848 0.84 RNASEL (0.68) RNASELP2RX1P2RX3P2RX2P2RX4
SCHEMBL5513986 0.84 RNASEL (0.51) RNASELP2RY11P2RY1DNPH1PRKAB2
SCHEMBL19260795 0.84 P2RY1 (0.66) P2RX1P2RX3P2RY11P2RX2P2RX4
SCHEMBL1122709 0.84 RNASEL (0.66) RNASELADORA1
Xylose SCHEMBL16969132 0.84 ENPP1 (0.61) RNASELP2RX1P2RX3P2RY11P2RX2
SCHEMBL31677489 0.83 RNASEL (0.76) RNASELP2RX1P2RX3P2RY11P2RX2
SCHEMBL31725154 0.83 DNPH1 (0.76) RNASELP2RY11P2RY1DNPH1PRKAB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed