SCHEMBL4329362

SCHEMBL4329362

CCCCCCCCCCCCN1C(=O)CCC1C

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 8/20 0.46
PTGER3 P43115 6/20 0.46
PTGER2 P43116 5/20 0.46
MGLL Q99685 2/20 0.45
FAAH O00519 1/20 0.45
GBA1 P04062 1/20 0.45
CHRM2 P08172 3/20 0.44
CHRM4 P08173 3/20 0.44
CHRM5 P08912 3/20 0.44
CHRM1 P11229 3/20 0.44
CHRM3 P20309 3/20 0.44
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 1/20 0.43
ALOX5 P09917 2/20 0.39
TP53 P04637 1/20 0.39
GAA P10253 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL664674 1.00 PTGER4 (0.46) PTGER4PTGER3PTGER2MGLLFAAH
SCHEMBL665342 1.00 PTGER4 (0.46) PTGER4PTGER3PTGER2MGLLFAAH
SCHEMBL664648 1.00 PTGER4 (0.46) PTGER4PTGER3PTGER2MGLLFAAH
SCHEMBL4588299 1.00 PTGER4 (0.46) PTGER4PTGER3PTGER2MGLLFAAH
SCHEMBL30697351 1.00 PTGER4 (0.46) PTGER4PTGER3PTGER2MGLLFAAH
SCHEMBL4588206 1.00 PTGER4 (0.46) PTGER4PTGER3PTGER2MGLLFAAH
SCHEMBL4588711 1.00 PTGER4 (0.46) PTGER4PTGER3PTGER2MGLLFAAH
SCHEMBL4635213 0.98 CHRM2 (0.45) PTGER4PTGER3PTGER2MGLLFAAH
Methane SCHEMBL4593708 0.96 CHRM2 (0.44) PTGER4PTGER3PTGER2MGLLFAAH
SCHEMBL1869119 0.93 MEN1 (0.48) PTGER4PTGER3PTGER2CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105296244-A Insulator electrified cleaning agent YANG CHAO 2016-02-03 CN claimed
CN-105296244-A Insulator electrified cleaning agent YANG CHAO 2016-02-03 CN disclosed
US-7612216-B2 Utilizing metal catalyst; one step; low cost E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-03 US disclosed
EP-1613573-A4 PRODUCTION OF 5-METHYL-1-HYDROCARBYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID DU PONT (US) 2008-10-29 EP disclosed
EP-1605934-A4 PRODUCTION OF 5-METHYL-N-(METHYL ARYL)-2-PYRROLIDONE, 5-METHYL-N-(METHYL CYCLOALKYL)-2-PYRROLIDONE AND 5-METHYL-N-ALKYL-2-PYRROLIDONE DU PONT (US) 2008-10-08 EP disclosed
EP-1605756-A4 PRODUCTION OF 5-METHYL-N-ARYL-2-PYRROLIDONE AND 5-METHYL-N-ALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID ESTERS WITH ARYL AND ALKYL AMINES DU PONT (US) 2008-08-13 EP disclosed
EP-1606252-A4 PRODUCTION OF N-(METHYL-ARYL)-2-LACTAM, N-(METHYL CYCLOAKLYL)-2-LACTAM AND N-ALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AND ALKYCYANO COMPOUNDS DU PONT (US) 2008-08-06 EP disclosed
EP-1605933-A4 PRODUCTION OF 5-METHYL-N-ARYL-2-PYRROLIDONE AND 5- METHYL-N-CYCLOALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID WITH ARYL AMINES DU PONT (US) 2008-07-02 EP disclosed
EP-1606046-A4 PRODUCTION OF 5-METHYL-N-(METHYL ARYL)-2-PYRROLIDONE, 5-METHYL-N-(METHYL CYCLOALKYL)-2-PYRROLIDONE AND 5- METHYL-N-ALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEUVLINIC ACID ESTERS WITH CYANO COMPOUNDS DU PONT (US) 2008-06-25 EP disclosed
EP-1605753-A4 PRODUCTION OF N-ARYL-2-LACTAM AND N-CYCLOALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AMINES DU PONT (US) 2008-03-12 EP disclosed
US-20040192936-A1 PRODUCTION OF N-ARYL-2-LACTAM AND N-ALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AND ALKYL NITRO COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY 2004-09-30 US disclosed
US-20040192932-A1 Production of N-(methyl aryl)-2-lactam, N-(Methyl cycloalkyl)-2-lactam and N-alkyl-2-lactam by reductive amination of lactones with aryl and alkyl cyano compounds E.I. DU PONT NEMOURS AND COMPANY 2004-09-30 US disclosed
US-20040108487-A1 FLUOROCARBON, OXYGENATED AND NON-OXYGENATED LUBRICANT, AND COMPATIBILIZER COMPOSITION, AND METHOD FOR REPLACING REFRIGERATION COMPOSITION IN A REFRIGERATION SYSTEM E.I. DU PONT DE NEMOURS AND COMPANY 2004-06-10 US disclosed
US-6743819-B1 METAL CATALYST E. I. DU PONTE DE NEMOURS AND COMPANY 2004-06-01 US disclosed
US-20040099838-A1 Refrigerant compositions comprising performance enhancing additives E. I. DU PONT DE NEMOURS AND COMPANY 2004-05-27 US disclosed
US-20040041122-A1 Fluorocarbon, oxygenated and non-oxygenated lubricant, and compatibilizer composition, and method for replacing refrigeration composition in a refrigeration system E.I. DU PONT DE NEMOURS AND COMPANY 2004-03-04 US disclosed
WO-2004015042-A2 REFRIGERANT COMPOSITIONS COMPRISING PERFORMANCE ENHANCING ADDITIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2004-02-19 WO disclosed
WO-2003104364-A1 FLUOROCARBON, OXYGENATED AND NON-OXYGENATED LUBRICANT, AND COMPATIBILIZER COMPOSITION, AND METHOD FOR REPLACING REFRIGERATION COMPOSITION IN A REFRIGERATION SYSTEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-12-18 WO disclosed
US-20030209688-A1 Refrigerant compositions containing a compatibilizer E. I. DU PONT DE NEMOURS AND COMPANY 2003-11-13 US disclosed
US-4171975-A MAGENTA COUPLER AND AN AMIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040192936-A1 PRODUCTION OF N-ARYL-2-LACTAM AND N-ALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AND ALKYL NITRO COMPOUNDS NIT2, NANS, ASNS PTGER4 2297/4885PTGER3 3788/4885PTGER2 1194/4885
US-20040192932-A1 Production of N-(methyl aryl)-2-lactam, N-(Methyl cycloalkyl)-2-lactam and N-alkyl-2-lactam by reductive amination of lactones with aryl and alkyl cyano compounds AAAS, ASNS, NIT2 PTGER4 2992/4885PTGER3 4155/4885PTGER2 1643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.