Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL664674 | 1.00 | PTGER4 (0.46) | PTGER4PTGER3PTGER2MGLLFAAH | |
| SCHEMBL665342 | 1.00 | PTGER4 (0.46) | PTGER4PTGER3PTGER2MGLLFAAH | |
| SCHEMBL4329362 | 1.00 | PTGER4 (0.46) | PTGER4PTGER3PTGER2MGLLFAAH | |
| SCHEMBL664648 | 1.00 | PTGER4 (0.46) | PTGER4PTGER3PTGER2MGLLFAAH | |
| SCHEMBL30697351 | 1.00 | PTGER4 (0.46) | PTGER4PTGER3PTGER2MGLLFAAH | |
| SCHEMBL4588206 | 1.00 | PTGER4 (0.46) | PTGER4PTGER3PTGER2MGLLFAAH | |
| SCHEMBL4588711 | 1.00 | PTGER4 (0.46) | PTGER4PTGER3PTGER2MGLLFAAH | |
| SCHEMBL4635213 | 0.98 | CHRM2 (0.45) | PTGER4PTGER3PTGER2MGLLFAAH | |
| Methane SCHEMBL4593708 | 0.96 | CHRM2 (0.44) | PTGER4PTGER3PTGER2MGLLFAAH | |
| SCHEMBL1869119 | 0.93 | MEN1 (0.48) | PTGER4PTGER3PTGER2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613573-A4 | PRODUCTION OF 5-METHYL-1-HYDROCARBYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID | DU PONT (US) | 2008-10-29 | — | — | EP | disclosed |
| US-7217373-B2 | Fluorocarbon, oxygenated and non-oxygenated lubricant, and compatibilizer composition, and method for replacing refrigeration composition in a refrigeration system | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-05-15 | — | — | US | disclosed |
| US-7157020-B2 | Refrigerant compositions comprising performance enhancing additives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| US-6991744-B2 | Refrigerant compositions containing a compatibilizer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-01-31 | — | — | US | disclosed |
| EP-1613573-A2 | PRODUCTION OF 5-METHYL-1-HYDROCARBYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-01-11 | — | — | EP | disclosed |
| US-6962665-B2 | Refrigerant compositions containing a compatibilizer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-11-08 | — | — | US | disclosed |
| US-20050178999-A1 | Fluorocarbon, oxygenated and non-oxygenated lubricant, and compatibilizer composition, and method for replacing refrigeration composition in a refrigeration system | MINOR BARBARA H (US) | 2005-08-18 | — | — | US | disclosed |
| EP-1551934-A2 | REFRIGERANT COMPOSITIONS COMPRISING PERFORMANCE ENHANCING ADDITIVES | E. I. du Pont de Nemours and Company (US) | 2005-07-13 | — | — | EP | disclosed |
| US-6900337-B2 | Production of 5-methyl-1-hydrocarbyl-2-pyrrolidone by reductive amination of levulinic acid | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-05-31 | — | — | US | disclosed |
| US-6899820-B2 | Fluorocarbon, oxygenated and non-oxygenated lubricant, and compatibilizer composition, and method for replacing refrigeration composition in a refrigeration system | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-05-31 | — | — | US | disclosed |
| WO-2004085349-A2 | PRODUCTION OF 5-METHYL-1-HYDROCARBYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2004-10-07 | — | — | WO | disclosed |
| US-20040192933-A1 | Production of 5-methyl-1-hydrocarbyl-2-pyrrolidone by reductive amination of levulinic acid | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
| EP-1451263-A1 | REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER AND USE THEREOF IN A COMPRESSION REFRIGERATION APPARATUS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-09-01 | — | — | EP | disclosed |
| US-20040108487-A1 | FLUOROCARBON, OXYGENATED AND NON-OXYGENATED LUBRICANT, AND COMPATIBILIZER COMPOSITION, AND METHOD FOR REPLACING REFRIGERATION COMPOSITION IN A REFRIGERATION SYSTEM | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-06-10 | — | — | US | disclosed |
| US-20040099838-A1 | Refrigerant compositions comprising performance enhancing additives | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-05-27 | — | — | US | disclosed |
| US-20040041122-A1 | Fluorocarbon, oxygenated and non-oxygenated lubricant, and compatibilizer composition, and method for replacing refrigeration composition in a refrigeration system | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-03-04 | — | — | US | disclosed |
| WO-2004015042-A2 | REFRIGERANT COMPOSITIONS COMPRISING PERFORMANCE ENHANCING ADDITIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |
| WO-2003104364-A1 | FLUOROCARBON, OXYGENATED AND NON-OXYGENATED LUBRICANT, AND COMPATIBILIZER COMPOSITION, AND METHOD FOR REPLACING REFRIGERATION COMPOSITION IN A REFRIGERATION SYSTEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |
| US-20030209688-A1 | Refrigerant compositions containing a compatibilizer | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-11-13 | — | — | US | disclosed |
| WO-2003050200-A1 | REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER AND USE THEROF IN A COMPRESSION REFRIGERATION APPARATUS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192933-A1 | Production of 5-methyl-1-hydrocarbyl-2-pyrrolidone by reductive amination of levulinic acid | ALDH18A1, PRMT5, PYCR1 | PTGER4 3406/4885PTGER3 3941/4885PTGER2 1700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.