Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 8/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL4593708 | 0.98 | CHRM2 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL30697351 | 0.98 | PTGER4 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL665342 | 0.98 | PTGER4 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4329362 | 0.98 | PTGER4 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4588299 | 0.98 | PTGER4 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4588711 | 0.98 | PTGER4 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4588206 | 0.98 | PTGER4 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL664674 | 0.98 | PTGER4 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL664648 | 0.98 | PTGER4 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL1869119 | 0.94 | MEN1 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114934082-B | Method for synthesizing (S) -5-methyl-2-pyrrolidone by continuous flow biocatalysis | 华东理工大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-114686451-B | Amine dehydrogenase mutant and application thereof in preparation of (S) -5-methyl-2-pyrrolidone | 华东理工大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-114934082-A | Method for continuous flow biocatalytic synthesis of (S) -5-methyl-2-pyrrolidone | 华东理工大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-114686451-A | Amine dehydrogenase mutant and application thereof in preparation of (S) -5-methyl-2-pyrrolidone | 华东理工大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-110294701-B | Synthetic method of 5-methyl-2-pyrrolidone or derivatives thereof | 厦门大学 | 2021-07-09 | — | — | CN | disclosed |
| CN-110615754-A | Synthetic method of 5-methyl-2-pyrrolidone | 浙江工业大学 | 2019-12-27 | — | — | CN | disclosed |
| EP-1605756-A4 | PRODUCTION OF 5-METHYL-N-ARYL-2-PYRROLIDONE AND 5-METHYL-N-ALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID ESTERS WITH ARYL AND ALKYL AMINES | DU PONT (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1605756-A4 | PRODUCTION OF 5-METHYL-N-ARYL-2-PYRROLIDONE AND 5-METHYL-N-ALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID ESTERS WITH ARYL AND ALKYL AMINES | DU PONT (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1605933-A4 | PRODUCTION OF 5-METHYL-N-ARYL-2-PYRROLIDONE AND 5- METHYL-N-CYCLOALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID WITH ARYL AMINES | DU PONT (US) | 2008-07-02 | — | — | EP | disclosed |
| EP-1605933-A4 | PRODUCTION OF 5-METHYL-N-ARYL-2-PYRROLIDONE AND 5- METHYL-N-CYCLOALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID WITH ARYL AMINES | DU PONT (US) | 2008-07-02 | — | — | EP | disclosed |
| US-20040192936-A1 | PRODUCTION OF N-ARYL-2-LACTAM AND N-ALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AND ALKYL NITRO COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
| US-20040192939-A1 | Production of 5-methyl-N-aryl-2-pyrrolidone and 5-methyl-N-cycloalkyl-2-pyrrolidone by reductive amination of levulinic acid with aryl amines | MANZER LEO ERNEST (US) | 2004-09-30 | — | — | US | disclosed |
| US-20040192939-A1 | Production of 5-methyl-N-aryl-2-pyrrolidone and 5-methyl-N-cycloalkyl-2-pyrrolidone by reductive amination of levulinic acid with aryl amines | MANZER LEO ERNEST (US) | 2004-09-30 | — | — | US | disclosed |
| US-20040192939-A1 | Production of 5-methyl-N-aryl-2-pyrrolidone and 5-methyl-N-cycloalkyl-2-pyrrolidone by reductive amination of levulinic acid with aryl amines | MANZER LEO ERNEST (US) | 2004-09-30 | — | — | US | disclosed |
| US-6743819-B1 | METAL CATALYST | E. I. DU PONTE DE NEMOURS AND COMPANY | 2004-06-01 | — | — | US | disclosed |
| US-6743819-B1 | METAL CATALYST | E. I. DU PONTE DE NEMOURS AND COMPANY | 2004-06-01 | — | — | US | disclosed |
| US-6743819-B1 | METAL CATALYST | E. I. DU PONTE DE NEMOURS AND COMPANY | 2004-06-01 | — | — | US | disclosed |
| EP-0938604-A4 | PROCESS FOR IMPROVING POLYAMIDE, ACRYLIC, ARAMID, CELLULOSIC AND POLYESTER PROPERTIES, AND MODIFIED POLYMERS PRODUCED THEREBY | INTERA TECHNOLOGIES INC (US) | 2000-11-22 | — | — | EP | disclosed |
| EP-0938604-A1 | PROCESS FOR IMPROVING POLYAMIDE, ACRYLIC, ARAMID, CELLULOSIC AND POLYESTER PROPERTIES, AND MODIFIED POLYMERS PRODUCED THEREBY | Intera Technologies, Inc. (US) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998012373-A1 | PROCESS FOR IMPROVING POLYAMIDE, ACRYLIC, ARAMID, CELLULOSIC AND POLYESTER PROPERTIES, AND MODIFIED POLYMERS PRODUCED THEREBY | INTERA TECHNOLOGIES, INC. (US) | 1998-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192939-A1 | Production of 5-methyl-N-aryl-2-pyrrolidone and 5-methyl-N-cycloalkyl-2-pyrrolidone by reductive amination of levulinic acid with aryl amines | PNPO, ASNS, PAH | CHRM2 1927/4885CHRM4 2361/4885CHRM5 550/4885 |
| US-20040192936-A1 | PRODUCTION OF N-ARYL-2-LACTAM AND N-ALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AND ALKYL NITRO COMPOUNDS | NIT2, NANS, ASNS | CHRM2 3392/4885CHRM4 3408/4885CHRM5 3471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.