Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341704 | 0.90 | GAA (0.49) | MEN1KMT2AGAAMMP1LDHA | |
| SCHEMBL4328684 | 0.87 | LDHA (0.41) | KMT2ASMN1; SMN2TACR1MMP1LDHA | |
| SCHEMBL4482826 | 0.86 | ALDH1A1 (0.41) | MEN1KMT2AGAAMMP1TSHR | |
| SCHEMBL4347011 | 0.85 | SMN1; SMN2 (0.39) | PTGDR2MAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6654698 | 0.84 | PTGDR2 (0.51) | PTGDR2MAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4328226 | 0.84 | MMP1 (0.44) | MEN1KMT2ASMN1; SMN2MMP1PPARG | |
| SCHEMBL4339373 | 0.84 | PPARA (0.48) | MEN1KMT2AMMP1PPARGPPARA | |
| SCHEMBL4332390 | 0.83 | KMT2A (0.48) | MAPK1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL4333270 | 0.83 | ALDH1A1 (0.47) | GAASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4335253 | 0.83 | MMP1 (0.40) | MMP1LDHANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |