SCHEMBL4329997

SCHEMBL4329997

C=C(C)C(=O)OCCNS(=O)(=O)CCC(F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
TSHR P16473 3/20 0.36
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841895 0.86 THRB (0.34) THRBTSHR
SCHEMBL14252451 0.84 THRB (0.33) THRBTSHR
SCHEMBL14252465 0.82 TSHR (0.33) THRBTSHR
SCHEMBL14252578 0.82 TSHR (0.33) THRBTSHR
SCHEMBL15836509 0.80 THRB (0.40) THRBTSHRALDH1A1
SCHEMBL4310911 0.80 THRB (0.40) THRBTSHRALDH1A1
SCHEMBL14252468 0.80 TSHR (0.32) THRBTSHR
SCHEMBL11418593 0.79 THRB (0.41) THRBTSHRALDH1A1
SCHEMBL12330291 0.78 THRB (0.43) THRBTSHRALDH1A1
SCHEMBL3256380 0.78 THRB (0.50) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137773-A1 Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Forming Foams, and Foam Stabilizers ASEPSIS, INC. 2009-05-28 US disclosed
US-20090137773-A1 Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Forming Foams, and Foam Stabilizers ASEPSIS, INC. 2009-05-28 US disclosed
US-20090137773-A1 Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Forming Foams, and Foam Stabilizers ASEPSIS, INC. 2009-05-28 US disclosed
EP-1907343-A2 PRODUCTION PROCESSES AND SYSTEMS, COMPOSITIONS, SURFACTANTS, MONOMER UNITS, METAL COMPLEXES, PHOSPHATE ESTERS, GLYCOLS, AQUEOUS FILM FORMING FOAMS, AND FOAM STABILIZERS GREAT LAKES CHEMICAL CORPORATION (US) 2008-04-09 EP disclosed
US-20080076892-A1 Telomer compositions and production processes E. I. DU PONT DE NEMOURS AND COMPANY 2008-03-27 US disclosed
US-20080076892-A1 Telomer compositions and production processes E. I. DU PONT DE NEMOURS AND COMPANY 2008-03-27 US disclosed
WO-2008019111-A2 TELOMER COMPOSITIONS AND PRODUCTION PROCESSES GREAT LAKES CHEMICAL CORPORATION (US) 2008-02-14 WO disclosed
WO-2007016359-A2 PRODUCTION PROCESSES AND SYSTEMS, COMPOSITIONS, SURFACTANTS, MONOMER UNITS, METAL COMPLEXES, PHOSPHATE ESTERS, GLYCOLS, AQUEOUS FILM FORMING FOAMS, AND FOAM STABILIZERS GREAT LAKES CHEMICAL CORPORATION (US) 2007-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137773-A1 Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Forming Foams, and Foam Stabilizers RFC3, RFC2, RFC4 THRB 4127/4885TSHR 2661/4885ALDH1A1 4356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.