Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330122 | 0.81 | KMT2A (0.47) | SMN1; SMN2L3MBTL1NPSR1KMT2AMAPT | |
| SCHEMBL17761183 | 0.76 | ALDH1A1 (0.54) | POLBL3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL4468269 | 0.75 | ABCG2 (0.44) | ABCB1ABCG2PLA2G1BSMN1; SMN2ATG4B | |
| SCHEMBL4451781 | 0.73 | KMT2A (0.52) | POLBKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL29519193 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBKMT2AGAATSHR | |
| SCHEMBL1226530 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBKMT2AGAATSHR | |
| SCHEMBL30006500 | 0.72 | ALDH1A1 (0.56) | POLBL3MBTL1MAPTTSHRALDH1A1 | |
| SCHEMBL1586233 | 0.72 | ALDH1A1 (0.56) | POLBL3MBTL1MAPTTSHRALDH1A1 | |
| SCHEMBL17028096 | 0.72 | HCRTR1 (0.39) | — | |
| SCHEMBL17028130 | 0.72 | HCRTR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |