Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.65 |
| ▸ | GSK3B | P49841 | 2/20 | 0.65 |
| ▸ | ENPP3 | O14638 | 8/20 | 0.58 |
| ▸ | ENPP1 | P22413 | 8/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578657 | 0.86 | ENPP3 (0.58) | PTPN1GSK3BENPP3ENPP1ENPP2 | |
| SCHEMBL4337232 | 0.86 | ALDH1A1 (0.59) | PTPN1GSK3BENPP3ENPP1ENPP2 | |
| SCHEMBL6550840 | 0.86 | ENPP3 (0.58) | PTPN1GSK3BENPP3ENPP1ENPP2 | |
| SCHEMBL26162976 | 0.83 | ENPP3 (0.63) | ENPP3ENPP1ENPP2CA1CA2 | |
| SCHEMBL13578628 | 0.82 | MEN1 (0.63) | ENPP3ENPP1ENPP2CA1CA2 | |
| SCHEMBL4342457 | 0.82 | GSK3B (0.62) | PTPN1GSK3BENPP3ENPP1ENPP2 | |
| SCHEMBL203931 | 0.81 | GSK3B (1.00) | PTPN1GSK3BHSD11B1 | |
| SCHEMBL4321294 | 0.80 | PTPN1 (0.64) | PTPN1GSK3BENPP3ENPP1ENPP2 | |
| SCHEMBL4487224 | 0.78 | ENPP3 (0.52) | PTPN1ENPP3ENPP1ENPP2CA1 | |
| SCHEMBL6306030 | 0.78 | ENPP3 (0.56) | ENPP3ENPP1ENPP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |