Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | RECQL | P46063 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ENPP1 | P22413 | 7/20 | 0.58 |
| ▸ | ENPP3 | O14638 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330199 | 0.86 | PTPN1 (0.65) | ALDH1A1RECQLMEN1KMT2AMAPT | |
| SCHEMBL4326069 | 0.85 | KMT2A (0.48) | ALDH1A1RECQLMEN1KMT2AMAPT | |
| SCHEMBL4342457 | 0.85 | GSK3B (0.62) | ALDH1A1MEN1KMT2AENPP1ENPP3 | |
| SCHEMBL919272 | 0.81 | GSK3B (0.66) | ALDH1A1RECQLMEN1KMT2AMAPT | |
| SCHEMBL4321294 | 0.80 | PTPN1 (0.64) | MEN1KMT2AMAPTENPP1ENPP3 | |
| SCHEMBL5150156 | 0.78 | ALDH1A1 (0.65) | ALDH1A1RECQLMEN1KMT2AMAPT | |
| SCHEMBL8067321 | 0.78 | ALDH1A1 (0.65) | ALDH1A1RECQLMEN1KMT2AMAPT | |
| SCHEMBL4334952 | 0.78 | ENPP1 (0.53) | MEN1KMT2AENPP1GSK3BCA2 | |
| SCHEMBL9310139 | 0.78 | ALDH1A1 (0.64) | ALDH1A1RECQLMEN1KMT2AMAPT | |
| SCHEMBL4326754 | 0.77 | MAPT (0.65) | ALDH1A1RECQLMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |