Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13750393 | 0.83 | ALOX5AP (0.62) | ALOX5APALOX5 | |
| SCHEMBL3582653 | 0.82 | ALOX5AP (0.69) | ALOX5APALOX5 | |
| SCHEMBL4323551 | 0.81 | ALOX5AP (0.60) | ALOX5AP | |
| SCHEMBL4320159 | 0.81 | ALOX5AP (0.62) | ALOX5APALOX5 | |
| SCHEMBL4235296 | 0.80 | ALOX5AP (0.78) | ALOX5APALOX5 | |
| SCHEMBL13757932 | 0.79 | ALOX5AP (0.71) | ALOX5APALOX5 | |
| SCHEMBL4315839 | 0.78 | ALOX5AP (0.85) | ALOX5AP | |
| SCHEMBL4236116 | 0.78 | ALOX5AP (1.00) | ALOX5AP | |
| SCHEMBL4317892 | 0.78 | ALOX5AP (0.57) | ALOX5AP | |
| SCHEMBL4327149 | 0.76 | ALOX5AP (0.56) | ALOX5APALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090197883-A1 | Diphenyl Substituted Cycloalkanes, Compositions Containing Such Compounds and Methods Of Use | MERCK SHARP & DOHME CORP. | 2009-08-06 | — | — | US | disclosed |
| US-20090197883-A1 | Diphenyl Substituted Cycloalkanes, Compositions Containing Such Compounds and Methods Of Use | MERCK SHARP & DOHME CORP. | 2009-08-06 | — | — | US | disclosed |
| US-20090197883-A1 | Diphenyl Substituted Cycloalkanes, Compositions Containing Such Compounds and Methods Of Use | MERCK SHARP & DOHME CORP. | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197883-A1 | Diphenyl Substituted Cycloalkanes, Compositions Containing Such Compounds and Methods Of Use | ALOX5, LTC4S, ALOX15B | ALOX5AP 16/4885ALOX5 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.