Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.62 |
| ▸ | VEGFA | P15692 | 1/20 | 0.59 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11969306 | 1.00 | SIGMAR1 (0.62) | SIGMAR1VEGFAEGLN1TMEM97OPRD1 | |
| SCHEMBL16416519 | 0.95 | VEGFA (0.64) | SIGMAR1VEGFAEGLN1TMEM97POLB | |
| SCHEMBL7984234 | 0.91 | SIGMAR1 (0.53) | SIGMAR1VEGFAEGLN1OPRD1POLB | |
| SCHEMBL11990378 | 0.89 | SIGMAR1 (0.61) | SIGMAR1VEGFAEGLN1TMEM97POLB | |
| SCHEMBL1257009 | 0.87 | SPHK1 (0.64) | OPRD1SPHK2SPHK1 | |
| SCHEMBL1051602 | 0.87 | SPHK1 (0.64) | OPRD1SPHK2SPHK1 | |
| SCHEMBL6342866 | 0.87 | SPHK1 (0.64) | OPRD1SPHK2SPHK1 | |
| SCHEMBL5967865 | 0.86 | OPRD1 (0.51) | SIGMAR1OPRD1 | |
| SCHEMBL11969174 | 0.86 | OPRD1 (0.51) | SIGMAR1OPRD1 | |
| SCHEMBL10682307 | 0.86 | MEN1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3970723-A1 | AMINOINDANE COMPOUNDS FOR USE IN TREATING UROLOGICAL PAIN | Asana BioSciences, LLC (US) | 2022-03-23 | — | — | EP | disclosed |
| EP-3363437-B1 | AMINOINDANE COMPOUNDS AND USE THEREOF IN TREATING PAIN | ENDO PHARMACEUTICALS SOLUTIONS (US) | 2021-07-28 | — | — | EP | disclosed |
| EP-3363437-B1 | AMINOINDANE COMPOUNDS AND USE THEREOF IN TREATING PAIN | ENDO PHARMACEUTICALS SOLUTIONS (US) | 2021-07-28 | — | — | EP | disclosed |
| CN-107540599-B | Aminoindane compounds and their use to treat pain | 阿萨纳生物科技有限责任公司 | 2021-06-04 | — | — | CN | disclosed |
| EP-3363437-A1 | AMINOINDANE COMPOUNDS AND USE THEREOF IN TREATING PAIN | Endo Pharmaceuticals Solutions Inc. (US) | 2018-08-22 | — | — | EP | disclosed |
| EP-2675787-B1 | AMINOINDANE COMPOUNDS AND USE THEREOF IN TREATING PAIN | ENDO PHARMACEUTICALS INC (US) | 2018-03-28 | — | — | EP | disclosed |
| EP-2675787-B1 | AMINOINDANE COMPOUNDS AND USE THEREOF IN TREATING PAIN | ENDO PHARMACEUTICALS INC (US) | 2018-03-28 | — | — | EP | disclosed |
| US-9375423-B2 | Use of aminoindane compounds in treating overactive bladder and interstitial cystitis | ASANA BIOSCIENCES, LLC (US) | 2016-06-28 | — | — | US | disclosed |
| US-9375423-B2 | Use of aminoindane compounds in treating overactive bladder and interstitial cystitis | ASANA BIOSCIENCES, LLC (US) | 2016-06-28 | — | — | US | disclosed |
| US-9375423-B2 | Use of aminoindane compounds in treating overactive bladder and interstitial cystitis | ASANA BIOSCIENCES, LLC (US) | 2016-06-28 | — | — | US | disclosed |
| EP-1185267-A4 | DERMAL ANESTHETIC AGENTS | BRIDGE PHARMA INC (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2000076510-A9 | DERMAL ANESTHETIC AGENTS | BRIDGE PHARMA INC (US) | 2002-07-04 | — | — | WO | disclosed |
| US-6413987-B1 | ANALGESICS | BRIDGE PHARMA, INC. | 2002-07-02 | — | — | US | disclosed |
| CN-1355700-A | Skin anesthetic | BRIDGE PHARMA INC (US) | 2002-06-26 | — | — | CN | disclosed |
| EP-1185267-A1 | DERMAL ANESTHETIC AGENTS | Bridge Pharma, Inc. (US) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000076510-A1 | DERMAL ANESTHETIC AGENTS | BRIDGE PHARMA, INC. (US) | 2000-12-21 | — | — | WO | disclosed |
| US-5607950-A | IRRITABLE BOWEL SYNDROME | PFIZER INC. (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0508988-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-03-02 | — | — | EP | disclosed |
| EP-0508988-A1 | MUSCARINIC RECEPTOR ANTAGONISTS. | PFIZER LTD (GB) | 1992-10-21 | — | — | EP | disclosed |
| WO-1991010647-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |