Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28500836 | 1.00 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CTSHRADRA1A | |
| SCHEMBL196657 | 0.87 | TSHR (0.50) | ADRA2AADRA2BADRA2CTSHRADRA1A | |
| SCHEMBL2944729 | 0.83 | ESR1 (0.45) | ADRA2AADRA2BADRA2CTSHRCYP1A2 | |
| SCHEMBL29160572 | 0.82 | GABRA1 (0.39) | TSHRCYP1A2CYP3A4GABRA1SLC6A2 | |
| SCHEMBL112222 | 0.80 | TRPA1 (0.46) | TSHRCYP1A2CYP3A4TP53CYP2C9 | |
| SCHEMBL29773079 | 0.80 | TRPA1 (0.46) | TSHRCYP1A2CYP3A4TP53CYP2C9 | |
| SCHEMBL57485 | 0.80 | TRPA1 (0.46) | TSHRCYP1A2CYP3A4TP53CYP2C9 | |
| SCHEMBL8313799 | 0.78 | GABRA1 (0.48) | TSHRCYP1A2CYP3A4CYP2C19GABRA1 | |
| SCHEMBL34433460 | 0.78 | GABRA1 (0.48) | TSHRCYP1A2CYP3A4CYP2C19GABRA1 | |
| SCHEMBL28827429 | 0.78 | GABRA1 (0.48) | TSHRCYP1A2CYP3A4CYP2C19GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281206-A1 | COPOLYMER POLYOLS AND A PROCESS FOR THE PRODUCTION THEREOF | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-11-12 | — | — | US | disclosed |
| EP-2041198-A1 | COPOLYMER POLYOLS AND A PROCESS FOR THE PRODUCTION THEREOF | Dow Global Technologies Inc. (US) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008005708-A1 | COPOLYMER POLYOLS AND A PROCESS FOR THE PRODUCTION THEREOF | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-01-10 | — | — | WO | disclosed |