Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6028852 | 0.79 | MAPK14 (0.50) | MAPK14ALOX5MAPK11USP2MAPK13 | |
| SCHEMBL4336708 | 0.78 | SMN1; SMN2 (0.48) | MAPK14ALOX5MAPK11MAPK13MAPK12 | |
| SCHEMBL6029540 | 0.77 | MAPK14 (0.46) | MAPK14MAPK11MAPK13MAPK12 | |
| SCHEMBL4336422 | 0.77 | MAPK14 (0.45) | MAPK14ALOX5MAPK11KCNH2MAPK13 | |
| SCHEMBL13893080 | 0.75 | LMNA (0.37) | — | |
| SCHEMBL4331652 | 0.73 | MAPK3 (0.46) | MAPK14MAPK11KCNH2 | |
| SCHEMBL4338680 | 0.72 | MAPK14 (0.67) | MAPK14ALOX5MAPK11KCNH2MAPK13 | |
| SCHEMBL4334250 | 0.71 | MAPK14 (0.67) | MAPK14MAPK11KCNH2MAPK13MAPK12 | |
| SCHEMBL4334246 | 0.71 | MAPK14 (1.00) | MAPK14ALOX5MAPK11MAPK13MAPK12 | |
| SCHEMBL4340894 | 0.69 | MAPK14 (0.46) | MAPK14ALOX5MAPK11MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192164-A1 | Treating agent of inflammatory bowel disease | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2009-07-30 | — | — | US | claimed |
| EP-2044957-A1 | TREATMENT AGENT FOR INFLAMMATORY BOWEL DISEASE | ASKA Pharmaceutical Co., Ltd. (JP) | 2009-04-08 | — | — | EP | claimed |
| US-20090192164-A1 | Treating agent of inflammatory bowel disease | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2009-07-30 | — | — | US | disclosed |
| US-20090192164-A1 | Treating agent of inflammatory bowel disease | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2009-07-30 | — | — | US | disclosed |
| US-20090192164-A1 | Treating agent of inflammatory bowel disease | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2009-07-30 | — | — | US | disclosed |
| EP-2044957-A1 | TREATMENT AGENT FOR INFLAMMATORY BOWEL DISEASE | ASKA Pharmaceutical Co., Ltd. (JP) | 2009-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192164-A1 | Treating agent of inflammatory bowel disease | MAPK6, SLC10A2, MAP3K6 | MAPK14 13/4885ALOX5 657/4885MAPK11 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.