SCHEMBL4336422

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6028828	0.80	SRC (0.49)	MAPK14ALOX5MAPK11MAPK13MAPK12
	SCHEMBL4331656	0.77	MAPK14 (0.54)	MAPK14ALOX5MAPK11MAPK13MAPK12
	SCHEMBL13893017	0.76	MAPK1 (0.38)	MAPK1MEN1KMT2AHSP90AA1
	SCHEMBL4331193	0.76	MAPK14 (0.54)	MAPK14ALOX5MAPK11MAPK13MAPK12
	SCHEMBL14519649	0.74	MAPK14 (0.48)	MAPK14ALOX5MAPK11MAPK13MAPK12
	SCHEMBL14519631	0.74	MAPK14 (0.50)	MAPK14ALOX5MAPK11MAPK13MAPK12
	SCHEMBL14519643	0.72	MAPK14 (0.48)	MAPK14ALOX5MAPK11MAPK13MAPK12
	SCHEMBL27473245	0.71	MEN1 (0.48)	MAPK1MEN1KMT2AROCK2ROCK1
	SCHEMBL6175653	0.69	SRC (0.50)	MAPK14ALOX5MAPK11MAPK13MAPK12
	SCHEMBL7237239	0.69	MMP13 (0.73)	SLC2A1SLC2A4SLC2A8MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.