SCHEMBL4331816

SCHEMBL4331816

CC(C)Oc1cc(CCl)ccc1CCl

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.49
TTR P02766 2/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
KCNH2 Q12809 2/20 0.35
TMEM97 Q5BJF2 2/20 0.35
SIGMAR1 Q99720 2/20 0.35
GAA P10253 3/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10088641 0.81 CSNK2A1 (0.72) CSNK2A1TTRMEN1KMT2ALMNA
SCHEMBL4522853 0.81 CSNK2A1 (0.45) CSNK2A1MEN1KMT2ALMNAKCNH2
SCHEMBL20818373 0.80 CSNK2A1 (0.40) CSNK2A1KCNH2TMEM97SIGMAR1
SCHEMBL10088644 0.78 CSNK2A1 (0.49) CSNK2A1TTRMEN1KMT2ALMNA
SCHEMBL3155854 0.75 SLC6A2 (0.43) MEN1KMT2ALMNAKDM4EPOLB
SCHEMBL7096982 0.74 TTR (0.39) TTR
SCHEMBL1390783 0.74 POLB (0.55) MEN1KMT2ALMNAKDM4EPOLB
SCHEMBL2872097 0.74 CSNK2A1 (0.42) CSNK2A1TTRMEN1KMT2ALMNA
SCHEMBL932902 0.73 RXRA (0.56) CSNK2A1
SCHEMBL932494 0.73 S1PR1 (0.47) CSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975710-B2 POLYMER ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2009-06-10 EP disclosed
EP-0975710-B1 POLYMER ELECTROLUMINESCENT DEVICE KONINKL PHILIPS ELECTRONICS NV (NL) 2003-09-10 EP disclosed
EP-1310540-A1 Polymer electroluminescent device Koninklijke Philips Electronics N.V. (NL) 2003-05-14 EP disclosed
US-20020001732-A1 POLYMER ELECTROLUMINESCENT DEVICE U.S. PHILIPS CORPORATION 2002-01-03 US disclosed
EP-0975710-A1 POLYMER ELECTROLUMINESCENT DEVICE Koninklijke Philips Electronics N.V. (NL) 2000-02-02 EP disclosed
WO-1999021936-A1 POLYMER ELECTROLUMINESCENT DEVICE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 1999-05-06 WO disclosed