Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 13/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5110876 | 0.84 | CSNK2A1 (0.44) | CSNK2A1HTR2ASLC6A4KCNH2GAA | |
| SCHEMBL4331816 | 0.81 | CSNK2A1 (0.49) | CSNK2A1KCNH2GAAMEN1LMNA | |
| SCHEMBL20818373 | 0.80 | CSNK2A1 (0.40) | CSNK2A1HTR2ASLC6A4KCNH2HTR2C | |
| SCHEMBL2152147 | 0.79 | TTR (0.47) | HTR2ASLC6A4KCNH2GAAKDM4C | |
| SCHEMBL7846116 | 0.78 | TSHR (0.48) | HTR2AGAATSHRHTR2CHTR2B | |
| SCHEMBL11223797 | 0.76 | NOS2 (0.49) | CSNK2A1HTR2ASLC6A4GAATSHR | |
| SCHEMBL5119565 | 0.76 | TSHR (0.46) | HTR2ASLC6A4KCNH2GAAKDM5A | |
| SCHEMBL7466628 | 0.76 | CSNK2A1 (0.42) | CSNK2A1HTR2AGAATSHRHTR2C | |
| SCHEMBL3155854 | 0.75 | SLC6A2 (0.43) | SLC6A4KCNH2TSHRTSPOALDH1A1 | |
| SCHEMBL25974456 | 0.75 | HTR2A (0.46) | CSNK2A1HTR2ASLC6A4KCNH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1864971-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2007-12-12 | — | — | EP | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | CSNK2A1 2721/4885HTR2A 4228/4885SLC6A4 1689/4885 |
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | CSNK2A1 1135/4885HTR2A 2880/4885SLC6A4 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.