Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331962 | 1.00 | MAPT (0.52) | MAPTTSHRPKMPOLBALDH1A1 | |
| SCHEMBL4337975 | 0.92 | PKM (0.50) | MAPTTSHRPKMALDH1A1HTR1A | |
| SCHEMBL4337977 | 0.92 | PKM (0.50) | MAPTTSHRPKMALDH1A1HTR1A | |
| SCHEMBL4334400 | 0.90 | CA1 (0.53) | MAPTTSHRPKMPOLBALDH1A1 | |
| SCHEMBL4334397 | 0.90 | CA1 (0.53) | MAPTTSHRPKMPOLBALDH1A1 | |
| SCHEMBL4331921 | 0.86 | PKM (0.46) | MAPTTSHRPKMPOLBALDH1A1 | |
| SCHEMBL4331926 | 0.86 | PKM (0.46) | MAPTTSHRPKMPOLBALDH1A1 | |
| SCHEMBL4329338 | 0.85 | ALDH1A1 (0.49) | MAPTTSHRPKMALDH1A1HTR1A | |
| SCHEMBL4329336 | 0.85 | ALDH1A1 (0.49) | MAPTTSHRPKMALDH1A1HTR1A | |
| SCHEMBL4335100 | 0.83 | PKM (0.48) | TSHRPKMPOLBALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474696-B1 | POLYMERISATION OF CYCLIC ETHERS | SECR DEFENCE BRIT (GB) | 1996-11-20 | — | — | EP | claimed |
| US-5313000-A | Polymerization of cyclic ethers | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE U.K. OF BRITAIN AND NORTHERN IRELAND (GB) | 1994-05-17 | — | — | US | claimed |
| EP-0474696-A1 | POLYMERISATION OF CYCLIC ETHERS. | SECR DEFENCE BRIT (GB) | 1992-03-18 | — | — | EP | claimed |
| WO-1990015092-A1 | POLYMERISATION OF CYCLIC ETHERS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1990-12-13 | — | — | WO | claimed |
| US-20090285849-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2009-11-19 | — | — | US | disclosed |
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-20090088506-A1 | SYNTHESIS OF ENERGETIC THERMOPLASTIC ELASTOMERS CONTAINING BOTH POLYOXIRANE AND POLYOXETANE BLOCKS | ALLIANT TECHSYSTEMS INC. (US) | 2009-04-02 | — | — | US | disclosed |
| US-7101955-B1 | Synthesis of energetic thermoplastic elastomers containing both polyoxirane and polyoxetane blocks | ALLIANT TECHSYSTEMS INC. (US) | 2006-09-05 | — | — | US | disclosed |
| US-20060157173-A1 | Synthesis of energetic thermoplastic elastomers containing both polyoxirane and polyoxetane blocks | ALLIANT TECHSYSTEMS INC. | 2006-07-20 | — | — | US | disclosed |
| US-20060074215-A1 | Synthesis of energetic thermoplastic elastomers containing oligomeric urethane linkages | ALLIANT TECHSYSTEMS INC. | 2006-04-06 | — | — | US | disclosed |
| US-6997997-B1 | Method for the synthesis of energetic thermoplastic elastomers in non-halogenated solvents | ALLIANT TECHSYSTEMS INC. (US) | 2006-02-14 | — | — | US | disclosed |
| US-20050069555-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2005-03-31 | — | — | US | disclosed |
| WO-2000034209-A9 | SYNTHESIS OF ENERGETIC THERMOPLASTIC ELASTOMERS CONTAINING BOTH POLYOXIRANE AND POLYOXETANE BLOCKS | CORDANT TECH INC (US) | 2001-08-16 | — | — | WO | disclosed |
| WO-2000034353-A9 | METHOD FOR THE SYNTHESIS OF THERMOPLASTIC ELASTOMERS IN NON-HALOGENATED SOLVENTS | CORDANT TECH INC (US) | 2000-11-30 | — | — | WO | disclosed |
| WO-2000034209-A2 | SYNTHESIS OF ENERGETIC THERMOPLASTIC ELASTOMERS CONTAINING BOTH POLYOXIRANE AND POLYOXETANE BLOCKS | CORDANT TECHNOLOGIES, INC. (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000034350-A2 | SYNTHESIS OF ENERGETIC THERMOPLASTIC ELASTOMERS CONTAINING OLIGOMERIC URETHANE LINKAGES | CORDANT TECHNOLOGIES, INC. (US) | 2000-06-15 | — | — | WO | disclosed |
| EP-0474696-B1 | POLYMERISATION OF CYCLIC ETHERS | SECR DEFENCE BRIT (GB) | 1996-11-20 | — | — | EP | disclosed |
| US-5313000-A | Polymerization of cyclic ethers | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE U.K. OF BRITAIN AND NORTHERN IRELAND (GB) | 1994-05-17 | — | — | US | disclosed |
| EP-0474696-A1 | POLYMERISATION OF CYCLIC ETHERS. | SECR DEFENCE BRIT (GB) | 1992-03-18 | — | — | EP | disclosed |
| WO-1990015092-A1 | POLYMERISATION OF CYCLIC ETHERS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1990-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285849-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | MAVS, IRF3, HAVCR2 | MAPT 3619/4885TSHR 2969/4885PKM 4105/4885 |
| US-20050069555-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | MAVS, IRF3, HAVCR2 | MAPT 3876/4885TSHR 2747/4885PKM 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.