Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583701 | 0.86 | LMNA (0.59) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL8483541 | 0.83 | ALDH1A1 (0.45) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL8075328 | 0.81 | LMNA (0.61) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL6387092 | 0.79 | — | — | |
| SCHEMBL2907872 | 0.79 | — | — | |
| SCHEMBL7863631 | 0.78 | LMNA (0.65) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL215336 | 0.77 | ALDH1A1 (0.60) | LMNAMAPTPPARGKMT2AALDH1A1 | |
| SCHEMBL5583012 | 0.77 | ALDH1A1 (0.60) | LMNAMAPTPPARGKMT2AALDH1A1 | |
| SCHEMBL8010768 | 0.77 | — | — | |
| SCHEMBL215335 | 0.77 | ALDH1A1 (0.60) | LMNAMAPTPPARGKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138778-A1 | CYCLOPROPYL BENZAMIDE DERIVATIVES AS INTERMEDIATES FOR CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2009-11-19 | — | — | WO | disclosed |
| EP-0047470-A1 | Method for immunochemical measurement | FUJI PHOTO FILM CO., LTD. (JP) | 1982-03-17 | — | — | EP | disclosed |