SCHEMBL433204

SCHEMBL433204

OP(O)(=S)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.52
CA4 P22748 2/20 0.52
CA5A P35218 1/20 0.52
ESR1 P03372 3/20 0.52
ESR2 Q92731 2/20 0.52
CFTR P13569 1/20 0.46
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HTT P42858 1/20 0.41
USP2 O75604 1/20 0.37
GAA P10253 1/20 0.37
NPSR1 Q6W5P4 2/20 0.35
HSP90AA1 P07900 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
GLA P06280 1/20 0.35
CA3 P07451 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4656194 0.97 ESR1 (0.50) CA2CA4CA5AESR1ESR2
SCHEMBL28382220 0.94 ESR1 (0.48) CA2CA4CA5AESR1ESR2
SCHEMBL28386973 0.94 ESR1 (0.48) CA2CA4CA5AESR1ESR2
SCHEMBL13997113 0.83 ALDH1A1 (0.56) ESR1ESR2ALOX15TSHRALDH1A1
SCHEMBL4926349 0.81 CA2 (0.52) CA2CA4CA5AESR1ESR2
Phosphine SCHEMBL28874033 0.77 ESR1 (0.48) CA2CA4CA5AESR1ESR2
SCHEMBL3066667 0.77 ESR1 (0.48) CA2CA4CA5AESR1ESR2
SCHEMBL8994040 0.77 ESR1 (0.48) CA2CA4CA5AESR1ESR2
SCHEMBL31485042 0.77 MEN1 (0.47) CA2CA4CA5AESR1ESR2
SCHEMBL517954 0.76 ESR1 (0.68) CA2CA4CA5AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946786-A Grease composition and method for producing same 中国石油化工股份有限公司 2024-04-30 CN claimed
CN-117946800-A Grease composition and method for producing same 中国石油化工股份有限公司 2024-04-30 CN claimed
CN-117917467-A Lubricating oil composition for electric automobile shock absorber and preparation method thereof 中国石油化工股份有限公司 2024-04-23 CN claimed
CN-117917465-A Worm gear oil composition and preparation method thereof 中国石油化工股份有限公司 2024-04-23 CN claimed
CN-117917418-A Organic sulfur-phosphorus compound, preparation method and application thereof 中国石油化工股份有限公司 2024-04-23 CN claimed
CN-117917466-A Lubricating oil composition for hybrid automobile engine and preparation method thereof 中国石油化工股份有限公司 2024-04-23 CN claimed
CN-111961252-B Fire retardant phenylphosphonyl methyl silicone cage-shaped ester amine compound and preparation method thereof 苏州科技大学 2022-04-26 CN claimed
CN-111961252-A Fire retardant phenylphosphonyl methyl silicone cage-shaped ester amine compound and preparation method thereof 苏州科技大学 2020-11-20 CN claimed
CN-109824728-A Thio phosphono heterocycle methylene ester compounds of two silicon of fire retardant phenylphosphonothioic acid and preparation method thereof 苏州科技大学 2019-05-31 CN claimed
CN-109824731-A Fire retardant phenylphosphonothioic acid two (silicic acid phosphono heterocycle methylene) ester compounds and preparation method thereof 苏州科技大学 2019-05-31 CN claimed
CN-105566386-A Phenylthiophosphonic bi-(tribromophenyl) ester compound and preparation method thereof UNIV SUZHOU SCIENCE & TECH 2016-05-11 CN claimed
CN-105541911-A Phenyl thiophosphinic acid diester (haloethyl) compound and preparation method thereof UNIV SUZHOU SCIENCE & TECH 2016-05-04 CN claimed
CN-105503948-A Di(tetrabromo bisphenol A) phenylphosphonothioate compound and preparation method thereof UNIV SUZHOU SCIENCE & TECH 2016-04-20 CN claimed
CN-102268043-B Sulfur-containing organic phosphine double-cage cyclic ester compound and preparation method thereof USTC UNIV SCIENCE TECH CN 2014-04-09 CN claimed
CN-102276653-B Sulphur-containing organic phosphine flame retardant compound and preparation method thereof USTC UNIV SCIENCE TECH CN 2013-12-18 CN claimed
CN-102276653-A Novel sulphur-containing organic phosphine flame retardant compound and preparation method thereof 2011-12-14 CN claimed
CN-102268043-A Sulfur-containing organic phosphine double-cage cyclic ester compound and preparation method thereof 2011-12-07 CN claimed
EP-1989184-B1 INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES DOW AGROSCIENCES LLC (US) 2011-07-06 EP claimed
WO-2006081441-A1 WASTE TREATMENT BY IN-CONTAINER VITRIFICATION GEOSAFE CORPORATION (US) 2006-08-03 WO claimed
EP-0069269-B1 ECTOPARASITICIDAL SPRAY FORMULATION BAYER AG (DE) 1986-08-20 EP claimed