Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926349 | 0.77 | CA2 (0.52) | ESR1ESR2CA2CA4CA5A | |
| SCHEMBL726307 | 0.77 | ESR1 (0.46) | ESR1ESR2CA2CA4CA5A | |
| SCHEMBL2502559 | 0.77 | ESR1 (0.46) | ESR1ESR2CA2CA4CA5A | |
| SCHEMBL433204 | 0.77 | CA2 (0.52) | ESR1ESR2CA2CA4CA5A | |
| SCHEMBL11144247 | 0.76 | LMNA (0.42) | ESR1ESR2CA2ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL4656194 | 0.74 | ESR1 (0.50) | ESR1ESR2CA2CA4CA5A | |
| SCHEMBL56861 | 0.74 | CA2 (0.65) | ESR1CA2CA4CA5ACFTR | |
| Biphenyl SCHEMBL1913601 | 0.74 | ALDH1A1 (0.53) | ESR1ESR2CA2CA4CA5A | |
| SCHEMBL11145389 | 0.72 | ESR1 (0.42) | ESR1ESR2CA2CA4CA5A | |
| Phosphine SCHEMBL28874033 | 0.72 | ESR1 (0.48) | ESR1ESR2CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214591-A2 | Process for the preparation of bifunctional tertiary aromatic phosphanoxides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-18 | — | — | EP | claimed |
| US-5502190-A | DEHYDROHALOGENATION IN THE PRESENCE OF PHASE TRANSFER CATALYST, SOLVENT AND ALKALI METAL HYDROXIDE | BAYER CORPORATION (US) | 1996-03-26 | — | — | US | disclosed |
| US-5120846-A | Process for preparing phosphorothioates and phosphonoates in a three-phase system | DOWELANCO (US) | 1992-06-09 | — | — | US | disclosed |
| US-4816605-A | Process for the preparation of bifunctional tertiary aromatic phosphine oxides | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-28 | — | — | US | disclosed |
| US-4814448-A | TERT-AMINE CATALYST, NONIONIC SURFACTANT | THE DOW CHEMICAL COMPANY (US) | 1989-03-21 | — | — | US | disclosed |
| US-4814451-A | Process for preparing phosphorothioates and phosphates and phosphonothioates and phosphonates | THE DOW CHEMICAL COMPANY (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0214591-A2 | Process for the preparation of bifunctional tertiary aromatic phosphanoxides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-18 | — | — | EP | disclosed |
| US-4444764-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1984-04-24 | — | — | US | disclosed |
| EP-0023841-B1 | 5 PYRIMIDINOL PHOSPHORUS ESTERS, AND METHODS FOR THEIR MANUFACTURE, COMPOSITIONS CONTAINING THOSE ESTERS AND THEIR USE AS PESTICIDES | THE DOW CHEMICAL COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4147866-A | Process for preparing phosphorothioates and phenylphosphonothioates | THE DOW CHEMICAL COMPANY (US) | 1979-04-03 | — | — | US | disclosed |
| US-4028439-A | QUATERNARY AMMONIUM SALT AND IMIDAZOLE CATALYSTS | THE DOW CHEMICAL COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4028439-A | QUATERNARY AMMONIUM SALT AND IMIDAZOLE CATALYSTS | THE DOW CHEMICAL COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4016225-A | WITH QUATERNARY AMMONIUM SALT AND 1,4-DIAZABICYCLO(2.2.2)OCTANE CATALYST | THE DOW CHEMICAL COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-4016225-A | WITH QUATERNARY AMMONIUM SALT AND 1,4-DIAZABICYCLO(2.2.2)OCTANE CATALYST | THE DOW CHEMICAL COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-4007197-A | QUATERNARY AMMONIUM OR PHOSPHONIUM SALT AND TERTIARY AMINE CATALYST | THE DOW CHEMICAL COMPANY (US) | 1977-02-08 | — | — | US | disclosed |
| US-4007197-A | QUATERNARY AMMONIUM OR PHOSPHONIUM SALT AND TERTIARY AMINE CATALYST | THE DOW CHEMICAL COMPANY (US) | 1977-02-08 | — | — | US | disclosed |
| US-3972887-A | QUATERNARY AMMONIUM SALT CATALYST | THE DOW CHEMICAL COMPANY (US) | 1976-08-03 | — | — | US | disclosed |
| US-3972887-A | QUATERNARY AMMONIUM SALT CATALYST | THE DOW CHEMICAL COMPANY (US) | 1976-08-03 | — | — | US | disclosed |
| US-3917621-A | Process for preparing phosphorothioates and phenylphosphonothioates | DOW CHEMICAL CO | 1975-11-04 | — | — | US | disclosed |
| US-3907815-A | Process for preparing phosphorothioates and phenylphosphonothioates | DOW CHEMICAL CO | 1975-09-23 | — | — | US | disclosed |