SCHEMBL4342985

SCHEMBL4342985

CC(C)Oc1ccccc1C(=O)OC(=O)Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.54
HPGD P15428 3/20 0.46
XBP1 P17861 1/20 0.46
ALDH1A1 P00352 4/20 0.44
ACHE P22303 1/20 0.44
MAPT P10636 4/20 0.43
LMNA P02545 3/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
GAA P10253 1/20 0.43
HSD17B10 Q99714 4/20 0.43
KDM4E B2RXH2 3/20 0.43
TSHR P16473 1/20 0.43
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 1/20 0.42
ALOX15 P16050 1/20 0.41
IDO1 P14902 1/20 0.41
TDO2 P48775 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27787798 0.88 IRAK4 (0.60) IRAK4HPGDXBP1ALDH1A1ACHE
SCHEMBL4332049 0.88 IRAK4 (0.64) IRAK4HPGDXBP1ALDH1A1ACHE
Bicarbonate SCHEMBL29983437 0.86 IRAK4 (0.58) IRAK4HPGDXBP1ALDH1A1ACHE
SCHEMBL27958806 0.84 IRAK4 (0.68) IRAK4HPGDXBP1ALDH1A1ACHE
SCHEMBL2228969 0.83 HPGD (0.56) HPGDXBP1ALDH1A1MAPTKMT2A
Bicarbonate SCHEMBL6654633 0.82 HPGD (0.55) HPGDXBP1ALDH1A1MAPTKMT2A
SCHEMBL4335276 0.82 ALDH1A1 (0.45) HPGDXBP1ALDH1A1MAPTKMT2A
SCHEMBL5689370 0.81 CTNNB1 (0.57) HPGDALDH1A1MAPTLMNAKMT2A
SCHEMBL27568908 0.80 IRAK4 (0.58) IRAK4ALDH1A1ACHEMAPTLMNA
SCHEMBL4334988 0.79 MAPT (0.46) HPGDXBP1ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247734-B1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-08-31 EP disclosed
US-10370491-B2 Preparation of highly heat-resistant (co)polycarbonates by the transesterification method COVESTRO DEUTSCHLAND AG (DE) 2019-08-06 US disclosed
US-20170369642-A1 Preparation of Highly Heat-Resistant (Co)Polycarbonates by the Transesterification Method COVESTRO DEUTSCHLAND AG (DE) 2017-12-28 US disclosed
EP-3247734-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD Covestro Deutschland AG (DE) 2017-11-29 EP disclosed
WO-2016116480-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO DEUTSCHLAND AG (DE) 2016-07-28 WO disclosed
US-20090117314-A1 PROCESS FOR THE PREPARATION OF POLYCARBONATE BY THE MELT TRANSESTERIFICATION METHOD BAYER MATERIALSCIENCE AG (DE) 2009-05-07 US disclosed