SCHEMBL4332474

SCHEMBL4332474

C=CCOP(OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88171 0.86
SCHEMBL11835527 0.83
SCHEMBL9248210 0.83
SCHEMBL10899385 0.83
SCHEMBL21416634 0.80 MEN1 (0.34) MEN1POLBKMT2A
SCHEMBL11667239 0.79
SCHEMBL9806606 0.78 ALDH1A1 (0.36) MEN1POLBKMT2A
SCHEMBL7164229 0.77
SCHEMBL10707995 0.77 TSHR (0.37) MEN1POLBKMT2A
SCHEMBL27674548 0.76 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606088-B Ultraviolet-resistant asphalt mastic macadam mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2024-04-02 CN claimed
CN-116606088-A Ultraviolet-resistant asphalt mastic macadam mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2023-08-18 CN claimed
CN-116606088-B Ultraviolet-resistant asphalt mastic macadam mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2024-04-02 CN disclosed
CN-116606088-A Ultraviolet-resistant asphalt mastic macadam mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2023-08-18 CN disclosed
US-11316201-B2 Additives to improve electrolyte performance in lithium ion battery SOLVAY SA (BE) 2022-04-26 US disclosed
CN-109705247-B Flame-retardant polyolefin and preparation method thereof, and method for improving compatibility of polyolefin and flame retardant and simultaneously enhancing flame retardance of polyolefin 中国科学技术大学 2020-05-12 CN disclosed
CN-109705247-A The method that the compatibility of fire retardant polyolefin and preparation method thereof and improvement polyolefin and fire retardant enhances its anti-flammability simultaneously 中国科学技术大学 2019-05-03 CN disclosed
US-20180301759-A1 ADDITIVES TO IMPROVE ELECTROLYTE PERFORMANCE IN LITHIUM ION BATTERY SOLVAY SA (BE) 2018-10-18 US disclosed
US-10074874-B2 Additives to improve electrolyte performance in lithium ion batteries SOLVAY SA (BE) 2018-09-11 US disclosed
US-9877908-B2 Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives DUKE UNIVERSITY (US) 2018-01-30 US disclosed
US-20170239160-A1 COSMETIC AND PHARMACEUTICAL COMPOSITIONS AND METHODS USING 2-DECARBOXY-2-PHOSPHINICO DERIVATIVES THE PROCTER & GAMBLE COMPANY 2017-08-24 US disclosed
US-20070287644-A1 LUBRICATING OIL COMPOSITION SHELL OIL COMPANY 2007-12-13 US disclosed
EP-1860175-A2 Lubricating oil composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2007-11-28 EP disclosed
US-20060247214-A1 Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives DUKE UNIVERSITY (US) 2006-11-02 US disclosed
US-20060105924-A1 Friction regulator for lubricating oil and lubricating oil composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-05-18 US disclosed
EP-1267806-B1 USE OF COSMETIC AND PHARMACEUTICAL COMPOSITIONS COMPRISING 2-DECARBOXY-2-PHOSPHINICO DERIVATIVES OF PROSTAGLANDINS UNIV DUKE (US) 2005-12-07 EP disclosed
EP-1489158-A1 FRICTION REGULATOR FOR LUBRICATING OIL AND LUBRICATING OIL COMPOSITION SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2004-12-22 EP disclosed
EP-1267806-A2 COSMETIC AND PHARMACEUTICAL COMPOSITIONS AND METHODS USING 2-DECARBOXY-2-PHOSPHINICO DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 2003-01-02 EP disclosed
US-20020013294-A1 Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives DUKE UNIVERSITY 2002-01-31 US disclosed
WO-2001074314-A2 COSMETIC AND PHARMACEUTICAL COMPOSITIONS AND METHODS USING 2-DECARBOXY-2-PHOSPHINICO DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 2001-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247214-A1 Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives BMP2, PLOD2, PTGDR2 MEN1 1384/4885POLB 775/4885KMT2A 2935/4885
US-20170239160-A1 COSMETIC AND PHARMACEUTICAL COMPOSITIONS AND METHODS USING 2-DECARBOXY-2-PHOSPHINICO DERIVATIVES BMP2, PLOD2, PTGDR2 MEN1 1384/4885POLB 775/4885KMT2A 2935/4885
US-20020013294-A1 Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives BMP2, PLOD2, PTGDR2 MEN1 1384/4885POLB 775/4885KMT2A 2935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.