Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.53 |
| ▸ | GSK3B | P49841 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3192548 | 0.84 | PTPN1 (0.50) | PTPN1GSK3BMEN1KMT2AKDM4E | |
| SCHEMBL8073630 | 0.82 | MEN1 (0.56) | PTPN1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4333412 | 0.81 | PTPN1 (0.71) | PTPN1GSK3BMEN1KMT2AKDM4E | |
| SCHEMBL15967018 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL22978747 | 0.80 | KDM4E (0.60) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL16131324 | 0.78 | ALDH1A1 (0.49) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL2261141 | 0.77 | PTPN1 (0.66) | PTPN1GSK3BMEN1KMT2AALDH1A1 | |
| Beta-Naphtoic Acid SCHEMBL4328136 | 0.77 | PTPN1 (0.63) | PTPN1GSK3BMEN1KMT2AKDM4E | |
| SCHEMBL4328140 | 0.75 | PTPN1 (0.53) | PTPN1GSK3BMEN1KMT2AKDM4E | |
| SCHEMBL4324217 | 0.74 | GSK3B (0.72) | PTPN1GSK3BMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1810976-B1 | BENZONAPHTHACENEGLYCOSIDE DERIVATIVE AND USE THEREOF | FUJIFILM CORP (JP) | 2014-08-27 | — | — | EP | claimed |
| US-20080027144-A1 | Benzonaphthacene Glycoside Derivative and Use Thereof | FUJIFILM CORPORATION (JP) | 2008-01-31 | — | — | US | claimed |
| EP-1810976-A1 | BENZONAPHTHACENEGLYCOSIDE DERIVATIVE AND USE THEREOF | FUJIFILM Corporation (JP) | 2007-07-25 | — | — | EP | claimed |
| US-6693091-B2 | CONTAINING PHOTOACTIVE, FLUORESCENT, OR RADIOACTIVE MOIETY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2004-02-17 | — | — | US | claimed |
| US-20030225052-A1 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2003-12-04 | — | — | US | claimed |
| US-20030194370-A1 | Analogs of terpene trilactones from ginkgo biloba for bioorganic and imaging studies | THE TRUSTEES OF COLUMBIA UNIVERSITY | 2003-10-16 | — | — | US | claimed |
| WO-2003082185-A2 | ANALOGS OF TERPENE TRILACTONES FROM GINKGO BILOBA AND RELATED COMPOUNDS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-10-09 | — | — | WO | claimed |
| EP-1810976-B1 | BENZONAPHTHACENEGLYCOSIDE DERIVATIVE AND USE THEREOF | FUJIFILM CORP (JP) | 2014-08-27 | — | — | EP | disclosed |
| WO-2012104225-A1 | DERIVATIZATION OF RADIOPHARMACEUTICALS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-08-09 | — | — | WO | disclosed |
| US-7732582-B2 | Benzonaphthacene glycoside derivative and use thereof | FUJIFILM CORPORATION (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20090156668-A1 | Ginkgolide Compounds, Compositions, And Extracts, And Uses Thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-06-18 | — | — | US | disclosed |
| US-7473788-B2 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-01-06 | — | — | US | disclosed |
| US-20080027144-A1 | Benzonaphthacene Glycoside Derivative and Use Thereof | FUJIFILM CORPORATION (JP) | 2008-01-31 | — | — | US | disclosed |
| US-20070098632-A1 | Analogs of terpene trilactones from ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2007-05-03 | — | — | US | disclosed |
| US-7145021-B2 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2006-12-05 | — | — | US | disclosed |
| WO-2005092324-A1 | GINKGOLIDE COMPOUNDS, COMPOSITIONS, EXTRACTS, AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2005-10-06 | — | — | WO | disclosed |
| US-6693091-B2 | CONTAINING PHOTOACTIVE, FLUORESCENT, OR RADIOACTIVE MOIETY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2004-02-17 | — | — | US | disclosed |
| US-20030225052-A1 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2003-12-04 | — | — | US | disclosed |
| US-20030194370-A1 | Analogs of terpene trilactones from ginkgo biloba for bioorganic and imaging studies | THE TRUSTEES OF COLUMBIA UNIVERSITY | 2003-10-16 | — | — | US | disclosed |
| WO-2003082185-A2 | ANALOGS OF TERPENE TRILACTONES FROM GINKGO BILOBA AND RELATED COMPOUNDS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070098632-A1 | Analogs of terpene trilactones from ginkgo biloba and related compounds and uses thereof | GRK5, GPR55, GPBAR1 | PTPN1 4551/4885GSK3B 1792/4885MEN1 3188/4885 |
| US-20030225052-A1 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | GPBAR1, GRK5, CNR1 | PTPN1 4654/4885GSK3B 1529/4885MEN1 3812/4885 |
| US-20080027144-A1 | Benzonaphthacene Glycoside Derivative and Use Thereof | SORD, PSAT1, SBDS | PTPN1 4265/4885GSK3B 2625/4885MEN1 2746/4885 |
| US-20090156668-A1 | Ginkgolide Compounds, Compositions, And Extracts, And Uses Thereof | PYGB, NLN, GRIN3B | PTPN1 4667/4885GSK3B 67/4885MEN1 249/4885 |
| US-20030194370-A1 | Analogs of terpene trilactones from ginkgo biloba for bioorganic and imaging studies | GRK4, GRK1, GNB1 | PTPN1 4777/4885GSK3B 369/4885MEN1 2708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.