SCHEMBL418527

SCHEMBL418527

O=C(Oc1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.68
TDP1 Q9NUW8 4/20 0.68
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
ALDH1A1 P00352 3/20 0.58
NSD2 O96028 1/20 0.58
KDM4E B2RXH2 2/20 0.53
PARP10 Q53GL7 1/20 0.53
ALOX5 P09917 1/20 0.51
PRSS1 P07477 1/20 0.51
ACR P10323 1/20 0.51
TMPRSS15 P98073 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
EGFR P00533 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
PKM P14618 1/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72201 0.96 MAPT (0.62) MAPTTDP1MEN1KMT2ACES2
SCHEMBL69953 0.96 MAPT (0.62) MAPTTDP1MEN1KMT2ACES2
SCHEMBL29637878 0.91 MAPT (0.57) MAPTTDP1MEN1KMT2ACES2
SCHEMBL10960357 0.91 MAPT (0.57) MAPTTDP1MEN1KMT2ACES2
SCHEMBL6054705 0.87 KMT2A (0.62) MAPTTDP1MEN1KMT2AALDH1A1
SCHEMBL14206802 0.86 NPC1 (0.62) MAPTTDP1MEN1KMT2ACES2
SCHEMBL4326711 0.86 MAPT (0.60) MAPTTDP1MEN1KMT2ACES2
SCHEMBL11649516 0.86 KMT2A (0.60) MAPTTDP1MEN1KMT2ACES2
SCHEMBL14981363 0.86 KMT2A (0.61) MAPTTDP1MEN1KMT2ACES2
SCHEMBL25694544 0.85 KMT2A (0.59) MAPTTDP1MEN1KMT2ACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5134189-A Isocyanate, Imino Compound, Polymeric Binder MITSUBISHI PAPER MILLS LIMITED (JP) 1992-07-28 US claimed
JP-4151290-A None JP disclosed
JP-62018288-A None JP disclosed
JP-1281983-A None JP disclosed
US-20240181797-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2024-06-06 US disclosed
EP-4313612-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD Ricoh Company, Ltd. (JP) 2024-02-07 EP disclosed
EP-4313611-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD Ricoh Company, Ltd. (JP) 2024-02-07 EP disclosed
EP-4297978-A1 COMPOSITIONS AND METHODS FOR SENSITIZING HEAT MEDIA Solenis Technologies Cayman, L.P. (CH) 2024-01-03 EP disclosed
EP-3575100-B1 RECORDING MATERIAL AND RECORDING SHEET NIPPON SODA CO (JP) 2023-11-15 EP disclosed
WO-2023153481-A1 THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2023-08-17 WO disclosed
US-4839332-A AMINO-SUBSTITUTED FLUORENE AND ACID; DISCOLORATION INHIBITON, CHEMICAL RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1989-06-13 US disclosed
US-4826807-A ELECTRON-DONATING CHROMOGEN AND ELECTRON-ACCEPTING COMPOUND FUJI PHOTO CO., LTD. (JP) 1989-05-02 US disclosed
US-4797385-A LEUCO DYES, STARCH PARTICLES FUJI PHOTO FILM CO., LTD. (JP) 1989-01-10 US disclosed
US-4791095-A ANTIFOGGING AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1988-12-13 US disclosed
US-4786629-A FACSIMILE TRANSMISSION, NONSTAINING FUJI PHOTO FILM CO., LTD. (JP) 1988-11-22 US disclosed
EP-0275203-A2 Heat-sensitive recording material containing color forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-07-20 EP disclosed
US-4758547-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-07-19 US disclosed
EP-0260996-A2 Heat-sensitive recording material containing color forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-03-23 EP disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed
JP-S6218288-A THERMAL RECORDING MATERIAL MITSUI TOATSU CHEM INC 1987-01-27 JP disclosed