Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 6/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923787 | 0.81 | TSHR (0.56) | TSHRSMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7198204 | 0.81 | TSHR (0.56) | TSHRSMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL632703 | 0.80 | SLC1A3 (0.43) | TSHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL9736825 | 0.79 | TSHR (0.71) | TSHRSMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL13333910 | 0.78 | TSHR (0.65) | TSHRSMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL28654216 | 0.78 | THRB (0.44) | TSHRALDH1A1FAAHAKR1B1 | |
| SCHEMBL9646933 | 0.78 | CTSK (0.47) | TSHR | |
| SCHEMBL27539621 | 0.77 | ALDH1A1 (0.52) | TSHRSMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL873430 | 0.77 | TSHR (1.00) | TSHRSMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6919607 | 0.77 | TSHR (0.44) | TSHRSMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010918-A2 | OPTICAL DEVICES | MEDICONTUR ORVOSTECHNIKAI KFT. (HU) | 2012-01-26 | — | — | WO | disclosed |