Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 3/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | CPA1 | P15085 | 2/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15450545 | 0.90 | POLB (0.61) | SMN1; SMN2L3MBTL1LMNATSHRPOLB | |
| SCHEMBL4221139 | 0.86 | TGFBR1 (0.57) | L3MBTL1MMEACECPA1ACE2 | |
| SCHEMBL13878717 | 0.86 | TGFBR1 (0.57) | L3MBTL1MMEACECPA1ACE2 | |
| SCHEMBL15488024 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1MMEACECPA1 | |
| SCHEMBL3769914 | 0.85 | L3MBTL1 (0.58) | L3MBTL1MMEACECPA1ACE2 | |
| SCHEMBL996291 | 0.85 | L3MBTL1 (0.58) | L3MBTL1MMEACECPA1ACE2 | |
| SCHEMBL996293 | 0.85 | L3MBTL1 (0.58) | L3MBTL1MMEACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL28046933 | 0.84 | L3MBTL1 (0.57) | L3MBTL1MMEACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL27371193 | 0.84 | L3MBTL1 (0.57) | L3MBTL1MMEACECPA1ACE2 | |
| SCHEMBL13878718 | 0.81 | ACE (0.60) | L3MBTL1MMEACEACE2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595994-A2 | PROCESS FOR PREPARING PYRANO - [2,3-C]PYRIDINE DERIVATIVES | Glaxo Group Limited (GB) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012012391-A2 | PROCESS FOR PREPARING PYRANO - [2,3-C]PYRIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2012-01-26 | — | — | WO | disclosed |