Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.57 |
| ▸ | ITGAV | P06756 | 1/20 | 0.57 |
| ▸ | MME | P08473 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | ACE | P12821 | 2/20 | 0.55 |
| ▸ | CPA1 | P15085 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3769914 | 1.00 | L3MBTL1 (0.58) | L3MBTL1ITGB3ITGAVMMECTSL | |
| SCHEMBL996291 | 1.00 | L3MBTL1 (0.58) | L3MBTL1ITGB3ITGAVMMECTSL | |
| Hydrochloric Acid SCHEMBL27371193 | 0.98 | L3MBTL1 (0.57) | L3MBTL1ITGB3ITGAVMMECTSL | |
| Hydrochloric Acid SCHEMBL28046933 | 0.98 | L3MBTL1 (0.57) | L3MBTL1ITGB3ITGAVMMECTSL | |
| SCHEMBL10964365 | 0.91 | MMP8 (0.56) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL7291638 | 0.89 | ITGB3 (0.54) | L3MBTL1ITGB3ITGAVCTSLCTSB | |
| SCHEMBL8244008 | 0.89 | ALDH1A1 (0.59) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL7460396 | 0.89 | POLB (0.64) | L3MBTL1ALDH1A1ALOX15 | |
| SCHEMBL10801015 | 0.88 | CTSL (0.54) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL15219608 | 0.88 | CTSL (0.52) | CTSLCTSBCTSSCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043313-A1 | REVERSIBLE THERMOCHROMIC COMPOSITION, MICROENCAPSULATED PIGMENT USING SAID REVERSIBLE THERMOCHROMIC COMPOSITION, WRITING TOOL, AND TOY | 三菱ケミカル株式会社 | 2024-02-29 | — | — | WO | disclosed |
| US-20180305297-A1 | DTPA PRODRUGS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2018-10-25 | — | — | US | disclosed |
| US-9969681-B2 | DTPA prodrugs, compositions thereof, and methods of using the same | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2018-05-15 | — | — | US | disclosed |
| US-20170088506-A1 | DTPA PRODRUGS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-30 | — | — | US | disclosed |
| US-9546129-B2 | DTPA prodrugs, compositions thereof, and methods of using the same | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2017-01-17 | — | — | US | disclosed |
| US-20150251991-A1 | DTPA PRODRUGS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2015-09-10 | — | — | US | disclosed |
| US-20140243411-A1 | TOPICAL DTPA PRODRUG FORMULATIONS AND METHODS OF USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2014-08-28 | — | — | US | disclosed |
| EP-2655322-A1 | PROCESS FOR PREPARING CHIRAL AMINO ACIDS | Diverchim (FR) | 2013-10-30 | — | — | EP | disclosed |
| WO-2013109323-A2 | TOPICAL DTPA PRODRUG FORMULATIONS AND METHODS OF USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-07-25 | — | — | WO | disclosed |
| US-20120198576-A1 | METHODS FOR MAKING EMBRYONIC CELLS, EMBRYOS, AND ANIMALS SENSITIZED TO STRESS | BRANDEIS UNIVERSITY (US) | 2012-08-02 | — | — | US | disclosed |
| US-20030040644-A1 | Synthesis of nitroalcohol diastereomers | PHARM-ECO LABORATORIES, INC. | 2003-02-27 | — | — | US | disclosed |
| US-6462221-B1 | 3-SUBSTITUTED-3-AMINO-2-HYDROXYPROPANOIC ACID SALT OR 1-NITRO-3-SUBSTITUTE-3-AMINO-2-HYDROXYPROPANOL DIASTEREOMERS OBTAINED FROM SIMULATED MOVING BED SEPARATION | PHARM-ECO LABORATORIES, INC. | 2002-10-08 | — | — | US | disclosed |
| EP-1159253-A2 | SYNTHESIS OF NITROALCOHOL DIASTEREOMERS | Johnson Matthey Pharmaceutical Materials Inc (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000050378-A9 | SYNTHESIS OF NITROALCOHOL DIASTEREOMERS | — | 2001-08-23 | — | — | WO | disclosed |
| EP-1078919-A1 | SYNTHESIS OF $g(a)-AMINO-$g(a)',$g(a)'-DIHALOKETONES AND PROCESS FOR THE PREPARATION OF $g(b)-AMINO ACID DERIVATIVES BY THE USE OF THE SAME | KANEKA CORPORATION (JP) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000050378-A2 | SYNTHESIS OF NITROALCOHOL DIASTEREOMERS | PHARM-ECO LABORATORIES, INC. (US) | 2000-08-31 | — | — | WO | disclosed |
| US-5847144-A | Process for manufacturing α,α'-diaminoalcohol | HOFFMANN-LA ROCHE INC. (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040644-A1 | Synthesis of nitroalcohol diastereomers | ALDH7A1, ADRA1A, ADH1A | L3MBTL1 2514/4885ITGB3 274/4885ITGAV 690/4885 |
| US-20180305297-A1 | DTPA PRODRUGS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | NAPEPLD, NAAA, DNPEP | L3MBTL1 3930/4885ITGB3 3781/4885ITGAV 4058/4885 |
| US-20170088506-A1 | DTPA PRODRUGS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | NAPEPLD, NAAA, DNPEP | L3MBTL1 3930/4885ITGB3 3781/4885ITGAV 4058/4885 |
| US-20150251991-A1 | DTPA PRODRUGS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | NAPEPLD, NAAA, DNPEP | L3MBTL1 3930/4885ITGB3 3781/4885ITGAV 4058/4885 |
| US-20140243411-A1 | TOPICAL DTPA PRODRUG FORMULATIONS AND METHODS OF USING THE SAME | CPA3, DNPEP, SLC16A1 | L3MBTL1 4853/4885ITGB3 3871/4885ITGAV 3477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.