Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411919 | 0.80 | MTNR1A (0.46) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL4619345 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL3156128 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL7593591 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL3279075 | 0.78 | MTNR1A (0.44) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL6659655 | 0.78 | KMT2A (0.53) | ALDH1A1KMT2AHTTNPSR1POLB | |
| SCHEMBL9032197 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL5143600 | 0.78 | KMT2A (0.50) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL5143601 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KMT2ANPC1RAB9AHTT | |
| SCHEMBL2724523 | 0.77 | NPSR1 (0.46) | ALDH1A1KMT2ANPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1784401-A | Novel fused triazolones and uses thereof | ASTRAZENECA AB (SE) | 2006-06-07 | — | — | CN | claimed |
| CN-113105751-B | Method for processing low aniline pigment diazo component | 浙江科隆颜料科技有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-113105751-A | Method for processing low-aniline pigment diazo component | 浙江科隆颜料科技有限公司 | 2021-07-13 | — | — | CN | disclosed |
| CN-100482663-C | Novel fused triazolones and the uses thereof | ASTRAZENECA AB SE (SE) | 2009-04-29 | — | — | CN | disclosed |
| US-20090018230-A1 | Yellow radiation curing inks | CIBA CORP. | 2009-01-15 | — | — | US | disclosed |
| CN-1784401-A | Novel fused triazolones and uses thereof | ASTRAZENECA AB (SE) | 2006-06-07 | — | — | CN | disclosed |
| US-4115450-A | COLOR FORMERS | CIBA-GEIGY CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4054718-A | Heat-sensitive recording material containing a malachite green color former | CIBA-GEIGY CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |