Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11870179 | 0.86 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AKMT2AHTT | |
| SCHEMBL5143601 | 0.81 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AKMT2AHTT | |
| SCHEMBL5143600 | 0.81 | KMT2A (0.50) | ALDH1A1NPC1RAB9AKMT2AHTT | |
| SCHEMBL4334073 | 0.80 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9AKMT2AHTT | |
| SCHEMBL3156128 | 0.79 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9AKMT2AHTT | |
| SCHEMBL15667384 | 0.78 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AKMT2AHTT | |
| SCHEMBL1561385 | 0.78 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9AKMT2AHTT | |
| SCHEMBL28179383 | 0.78 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AKMT2AHTT | |
| SCHEMBL7364286 | 0.77 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AKMT2AHTT | |
| SCHEMBL3154354 | 0.76 | TP53 (0.62) | ALDH1A1NPC1RAB9AKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020012975-A1 | Production of amino acids and enzymes used therefor | PAGE MICHAEL IVAN (GB) | 2002-01-31 | — | — | US | disclosed |
| US-6268185-B1 | BY ENANTIOSELECTIVE CONVERSION OF A RACEMIC MIXTURE OF ALPHA-AMINO AMIDES TO THE CORRESPONDING ALPHA-AMINO ACID USING AN AMIDASE ENZYME FROM SPECIFIC RHODOCOCCUS CULTURE | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 2001-07-31 | — | — | US | disclosed |
| EP-0910661-A1 | PRODUCTION OF AMINO ACIDS AND ENZYMES USED THEREFOR | Ciba Specialty Chemicals Water Treatments Limited (GB) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998004733-A1 | PRODUCTION OF AMINO ACIDS AND ENZYMES USED THEREFOR | ALLIED COLLOIDS LIMITED (GB) | 1998-02-05 | — | — | WO | disclosed |