Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | L1CAM | P32004 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29905822 | 1.00 | CA1 (0.53) | CA1CA9KDM4EHIF1ASMN1; SMN2 | |
| SCHEMBL3389986 | 0.82 | HPGD (0.57) | CA1CA9KDM4EHIF1ASMN1; SMN2 | |
| SCHEMBL77381 | 0.79 | CA1 (0.77) | CA1CA9KDM4EHIF1ASMN1; SMN2 | |
| SCHEMBL6639039 | 0.79 | CA1 (0.64) | CA1CA9KDM4EHIF1ASMN1; SMN2 | |
| SCHEMBL4386922 | 0.77 | NAAA (0.59) | CA1CA9KDM4EHIF1ASMN1; SMN2 | |
| SCHEMBL1147664 | 0.77 | TSHR (0.73) | CA9KDM4EHIF1AMPOCYP2D6 | |
| SCHEMBL8344108 | 0.76 | CA12 (0.66) | CA9KDM4EHIF1AMPOCYP2D6 | |
| SCHEMBL6638962 | 0.75 | CA1 (0.51) | CA1CA9KDM4EHIF1ASMN1; SMN2 | |
| SCHEMBL8347813 | 0.74 | CA12 (0.64) | CA9KDM4EHIF1AMPOCYP2D6 | |
| SCHEMBL27912694 | 0.74 | HIF1A (0.68) | CA1CA9KDM4EHIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054565-A1 | Flame-Retardant plastics molding composition | CLARIANT INTERNATIONAL LTD. | 2009-02-26 | — | — | US | disclosed |
| EP-2028227-A1 | Flame-resistant plastic moulding material | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-25 | — | — | EP | disclosed |
| EP-0576833-B1 | Process for preparing hydrolytically stable trivalent phosphorus compounds and their use as stabilisers for thermoplastic materials | CLARIANT GMBH (DE) | 2001-03-07 | — | — | EP | disclosed |
| US-6043254-A | ANTIPROLIFERATIVE AGENT; ENZYME INHIBITOR | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0517128-B1 | Use of a carboxylic acid anhydride to manufacture a polyolefin moulding composition | ELENAC GMBH (DE) | 2000-01-26 | — | — | EP | disclosed |
| US-6013706-A | Process for the preparation of hyrolysis-stable trivalent phosphorus compounds and their use as stabilizers for thermoplastics | CLARIANT GMBH (DE) | 2000-01-11 | — | — | US | disclosed |
| EP-0668283-B1 | Process for the preparation of polyalkyl-1-oxadiazaspirodecane compounds | CLARIANT GMBH (DE) | 1998-05-20 | — | — | EP | disclosed |
| EP-0584567-B1 | Fire retardant polymer compositions with increased stability | CLARIANT GMBH (DE) | 1998-01-28 | — | — | EP | disclosed |
| US-5594142-A | USING SOLVENT MIXTURE AND BASIC CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| US-5550242-A | REACTION CARRIED OUT IN INERT ORGANIC SOLVENT IN PRESENCE OF SOLID ALKALI METAL HYDROXIDE OR A MIXTURE OF HYDROXIDE AND WATER; AVOIDS USE OF PHASE TRANSFER CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-27 | — | — | US | disclosed |
| US-5331034-A | Deactivation of catalyst residues with ditrimethylolpropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-19 | — | — | US | disclosed |
| EP-0599284-A1 | Cyclo-olefin polymer moulding composition with improved stability against chemical degradation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-01 | — | — | EP | disclosed |
| EP-0584567-A2 | Fire retardant polymer compositions with increased stability | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-02 | — | — | EP | disclosed |
| EP-0576833-A2 | Process for preparing hydrolytically stable trivalent phosphorus compounds and their use as stabilisators for thermoplastic materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-05 | — | — | EP | disclosed |
| EP-0214935-B1 | STERICALLY HINDERED SILICON ESTER STABILIZERS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | disclosed |
| EP-0517128-A2 | Use of a carboxylic acid anhydride to manufacture a polyolefin moulding composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-09 | — | — | EP | disclosed |
| US-5109043-A | Reacting 4,4'-dihalobiphenyl with suspension of finely divided magnesium to form grignard reagent | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-04-28 | — | — | US | disclosed |
| WO-1991002738-A1 | ARYL ESTER AMIDE HALIDES OF PHOSPHONOUS ACID, ARYL ESTER AMIDES OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-07 | — | — | WO | disclosed |
| EP-0214935-A2 | Sterically hindered silicon ester stabilizers | CIBA-GEIGY AG (CH) | 1987-03-18 | — | — | EP | disclosed |
| EP-0110820-A1 | Amino-substituted dibenzodioxaphosphepines and dioxaphosphocines | CIBA-GEIGY AG (CH) | 1984-06-13 | — | — | EP | disclosed |