Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | L1CAM | P32004 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636469 | 0.92 | NAAA (0.73) | NAAACA1CA9HDAC3HDAC1 | |
| SCHEMBL8934416 | 0.90 | NAAA (0.70) | NAAACA1CA9HDAC3HDAC1 | |
| SCHEMBL6634756 | 0.88 | HDAC3 (0.70) | NAAACA1CA9HDAC3HDAC1 | |
| SCHEMBL4386920 | 0.87 | NAAA (0.66) | NAAACA1CA9HDAC3HDAC1 | |
| SCHEMBL259037 | 0.86 | NAAA (0.47) | NAAACA1CA9HDAC3HDAC1 | |
| SCHEMBL823552 | 0.81 | NAAA (0.84) | NAAAKDM4ESMN1; SMN2GAAMPO | |
| SCHEMBL77381 | 0.80 | CA1 (0.77) | CA1CA9KDM4ESMN1; SMN2GAA | |
| SCHEMBL6639039 | 0.80 | CA1 (0.64) | NAAACA1CA9KDM4ESMN1; SMN2 | |
| SCHEMBL29417865 | 0.77 | L3MBTL1 (0.59) | NAAACA1CA9KDM4ESMN1; SMN2 | |
| SCHEMBL29905822 | 0.77 | CA1 (0.53) | CA1CA9KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1449864-B1 | CRYSTALLINE POLYGLYCOLIC ACID,POLYGLYCOLIC ACID COMPOSITION AND PROCESSES FOR PRODUCTION OF BOTH | KUREHA CORP (JP) | 2009-12-02 | — | — | EP | claimed |