SCHEMBL4334343

SCHEMBL4334343

COc1ccccc1-c1cc(CCl)ccc1CCl

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 18/20 0.53
HTR1A P08908 13/20 0.51
HTR2B P41595 13/20 0.51
HTR5A P47898 12/20 0.51
HTR1D P28221 11/20 0.51
HTR2A P28223 11/20 0.51
HTR1B P28222 10/20 0.51
HTR6 P50406 8/20 0.51
HTR2C P28335 7/20 0.51
HTR1E P28566 6/20 0.51
HTR3A P46098 1/20 0.51
TTR P02766 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18496497 0.83 HTR7 (0.49) HTR7HTR1AHTR2BHTR5AHTR1D
SCHEMBL7097664 0.81 GCGR (0.41) HTR7HTR1AHTR2BHTR5AHTR1D
SCHEMBL19002950 0.81 CSNK2A2 (0.38) TTR
SCHEMBL30023409 0.81 CSNK2A2 (0.38) TTR
SCHEMBL4348145 0.78 HTR7 (0.36) HTR7TTR
SCHEMBL21257555 0.77 TTR (0.59) HTR7HTR1AHTR2BHTR5AHTR1D
SCHEMBL7504815 0.75 HTR7 (0.68) HTR7HTR1ATTR
SCHEMBL5598123 0.73 TTR (0.54) TTR
SCHEMBL30776597 0.73 TTR (0.54) TTR
SCHEMBL3772032 0.72 MAOB (0.47) TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975710-B2 POLYMER ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2009-06-10 EP disclosed
EP-0975710-B1 POLYMER ELECTROLUMINESCENT DEVICE KONINKL PHILIPS ELECTRONICS NV (NL) 2003-09-10 EP disclosed
EP-1310540-A1 Polymer electroluminescent device Koninklijke Philips Electronics N.V. (NL) 2003-05-14 EP disclosed
US-20020001732-A1 POLYMER ELECTROLUMINESCENT DEVICE U.S. PHILIPS CORPORATION 2002-01-03 US disclosed