Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30023409 | 1.00 | CSNK2A2 (0.38) | CSNK2A2CSNK2BCSNK2A1CSNK2A3DPP4 | |
| SCHEMBL4348145 | 0.85 | HTR7 (0.36) | CSNK2A2CSNK2BCSNK2A1CSNK2A3TTR | |
| SCHEMBL19002938 | 0.82 | DPP4 (0.40) | CSNK2A2CSNK2BCSNK2A1CSNK2A3DPP4 | |
| SCHEMBL736614 | 0.82 | DPP4 (0.46) | CSNK2A2CSNK2BCSNK2A1CSNK2A3DPP4 | |
| SCHEMBL4345051 | 0.82 | CSNK2A1 (0.42) | CSNK2A1DPP4TTRALDH1A1TSHR | |
| SCHEMBL4334343 | 0.81 | HTR7 (0.53) | TTR | |
| SCHEMBL10896807 | 0.79 | DPP4 (0.44) | CSNK2A2CSNK2BCSNK2A1CSNK2A3DPP4 | |
| SCHEMBL1308849 | 0.77 | DPP4 (0.43) | DPP4ALDH1A1TSHRKMT2A | |
| SCHEMBL1309290 | 0.76 | HTR7 (0.41) | DPP4TSHRMAPK1 | |
| SCHEMBL4329358 | 0.76 | PTGER4 (0.41) | CSNK2A1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507269-B1 | STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT | EASTMAN CHEM CO (US) | 2020-09-23 | — | — | EP | disclosed |
| EP-3507269-A1 | STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT | Eastman Chemical Company (US) | 2019-07-10 | — | — | EP | disclosed |
| WO-2018044827-A1 | STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT | EASTMAN CHEMICAL COMPANY (US) | 2018-03-08 | — | — | WO | disclosed |
| US-9687837-B1 | Stable hydroformylation catalyst for preparation of high N/Iso ratio aldehyde product | EASTMAN CHEMICAL COMPANY (US) | 2017-06-27 | — | — | US | disclosed |