SCHEMBL4348145

SCHEMBL4348145

Cc1ccccc1-c1cc(CCl)ccc1CCl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 4/20 0.36
TTR P02766 1/20 0.35
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
CSNK2A1 P68400 1/20 0.34
CSNK2A3 Q8NEV1 1/20 0.34
FFAR1 O14842 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
MAPK1 P28482 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19462716 0.87 HTR7 (0.45) HTR7TTRMAPK1L3MBTL1ALDH1A1
SCHEMBL30023409 0.85 CSNK2A2 (0.38) TTRCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL19002950 0.85 CSNK2A2 (0.38) TTRCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL3943893 0.81 KMT2A (0.37) HTR7FFAR1FFAR4ALDH1A1MAPT
SCHEMBL4334343 0.78 HTR7 (0.53) HTR7TTR
SCHEMBL6626252 0.76 MYC (0.49) FFAR1FFAR4ALDH1A1PPARGPPARA
SCHEMBL4345051 0.76 CSNK2A1 (0.42) TTRCSNK2A1FFAR1FFAR4ALDH1A1
SCHEMBL6914100 0.74 ESR1 (0.37) TTRMAPK1RAB9ACYP2C19CYP3A4
SCHEMBL4349827 0.73 BACE1 (0.42) FFAR1FFAR4NPC1RAB9ASMN1; SMN2
SCHEMBL19462642 0.73 HTR7 (0.65) HTR7FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975710-B2 POLYMER ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2009-06-10 EP disclosed
EP-0975710-B1 POLYMER ELECTROLUMINESCENT DEVICE KONINKL PHILIPS ELECTRONICS NV (NL) 2003-09-10 EP disclosed
EP-1310540-A1 Polymer electroluminescent device Koninklijke Philips Electronics N.V. (NL) 2003-05-14 EP disclosed
US-20020001732-A1 POLYMER ELECTROLUMINESCENT DEVICE U.S. PHILIPS CORPORATION 2002-01-03 US disclosed
EP-0975710-A1 POLYMER ELECTROLUMINESCENT DEVICE Koninklijke Philips Electronics N.V. (NL) 2000-02-02 EP disclosed
WO-1999021936-A1 POLYMER ELECTROLUMINESCENT DEVICE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 1999-05-06 WO disclosed