Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27783381 | 0.91 | TRPA1 (0.77) | TRPA1ATMMAPTHSD17B10TP53 | |
| Phosphoric Acid SCHEMBL28820986 | 0.91 | TRPA1 (0.77) | TRPA1ATMMAPTHSD17B10TP53 | |
| Methylamine SCHEMBL27475710 | 0.84 | TRPA1 (0.90) | TRPA1ATMMAPTHSD17B10TP53 | |
| SCHEMBL5940935 | 0.84 | TRPA1 (1.00) | TRPA1ATMMAPTHSD17B10TP53 | |
| SCHEMBL3498 | 0.84 | — | — | |
| SCHEMBL29622820 | 0.84 | — | — | |
| Urea SCHEMBL27830499 | 0.83 | TRPA1 (0.77) | TRPA1ATMMAPTHSD17B10TP53 | |
| Formaldehyde SCHEMBL3312486 | 0.82 | TRPA1 (0.85) | TRPA1ATMMAPTHSD17B10TP53 | |
| Ammonia Solution, Strong SCHEMBL3744582 | 0.82 | TRPA1 (0.94) | TRPA1ATMMAPTHSD17B10TP53 | |
| SCHEMBL5658340 | 0.82 | TRPA1 (0.94) | TRPA1ATMMAPTHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815834-B2 | Use of dendrimers to stimulate cell growth | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-08-26 | — | — | US | disclosed |
| US-20090142316-A1 | Use of Dendrimers to Stimulate Cell Growth | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090142316-A1 | Use of Dendrimers to Stimulate Cell Growth | HDGF, CD40LG, PPIP5K2 | TRPA1 3912/4885ATM 2498/4885MAPT 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.