Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CEL | P19835 | 2/20 | 0.33 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457959 | 0.90 | PTGS1 (0.31) | OPRL1 | |
| SCHEMBL434305 | 0.83 | ABCB1 (0.38) | CELALOX15BALDH1A1OPRL1NPC1 | |
| SCHEMBL435217 | 0.83 | OPRL1 (0.36) | CELOPRL1 | |
| SCHEMBL10693537 | 0.74 | SMN1; SMN2 (0.47) | CELALDH1A1OPRL1SMN1; SMN2 | |
| SCHEMBL3958803 | 0.72 | CYP2D6 (0.32) | CELCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL435126 | 0.71 | CEL (0.40) | CELALOX15BALDH1A1OPRL1NPC1 | |
| SCHEMBL10568941 | 0.68 | CEL (0.35) | CEL | |
| SCHEMBL3956673 | 0.68 | — | — | |
| SCHEMBL3796466 | 0.68 | CEL (0.44) | CELOPRL1SMN1; SMN2 | |
| SCHEMBL12290554 | 0.67 | SMN1; SMN2 (0.48) | CELALDH1A1OPRL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| US-5174997-A | Fungicides tolerated by plants | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-29 | — | — | US | disclosed |