SCHEMBL4334983

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4343158	0.87	MAPK10 (0.54)	MAPK10NPC1RAB9ASIRT2SIRT1
	SCHEMBL4338569	0.83	ADORA3 (0.46)	NPC1RAB9ASMN1; SMN2TP53ALDH1A1
	SCHEMBL4345714	0.81	MAPK10 (0.46)	MAPK10SMN1; SMN2SIRT2SIRT1POLB
	SCHEMBL4337637	0.77	MAPK1 (0.45)	MAPK10NPC1RAB9ASMN1; SMN2TP53
	SCHEMBL4329385	0.76	STK33 (0.44)	MAPK10NPC1RAB9ASMN1; SMN2ALDH1A1
	SCHEMBL2862233	0.76	MEN1 (0.45)	MAPK10NPC1RAB9ASMN1; SMN2TP53
	SCHEMBL2857326	0.76	PIP5K1C (0.48)	MAPK10NPC1RAB9ASMN1; SMN2TP53
	SCHEMBL4335786	0.74	MAPK10 (0.52)	MAPK10SIRT2SIRT1ALDH1A1KDM4E
	SCHEMBL2861026	0.73	TNIK (0.49)	MAPK10SIRT2SIRT1
	SCHEMBL2859049	0.73	MAPK10 (0.43)	MAPK10SIRT2SIRT1PIP5K1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.